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Intrinsic Pathway for Apoptosis

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Catalog number Product name Quantity
AA0002 Apoptosis antibody array includes 73 highly specific and well-characterized antibodies in the apoptosis pathway. 2 Pieces/Box
orb81171 Human Intrinsic Factor protein Intrinsic Facor Human Recombinant produced in baculovirus is glycosylated, polypeptide chain containing having a molecular mass of 55,000 Dalton. The Intrinsic Facor is 2
EIAAB09968 460 kDa receptor,Cubilin,CUBN,Homo sapiens,Human,IFCR,Intestinal intrinsic factor receptor,Intrinsic factor-cobalamin receptor,Intrinsic factor-vitamin B12 receptor
orb81883 Intrinsic Factor, Pig protein Intrinsic Factor is a purified protein_bioactive peptide. For research use only. 100
26-685 AIFM3 induces apoptosis through a caspase dependent pathway. AIFM3 reduces mitochondrial membrane potential. 0.05 mg
20-783-73410 MOUSE ANTI PORCINE INTRINSIC FACTOR - Intrinsic factor; IF; INF Monoclonal 0.2 mg
SCH-5390-0004 NATIVE PIG INTRINSIC FACTOR, Product Type Purified Protein, Specificity INTRINSIC FACTOR, Target Species Pig, Host N_A, Format Purified, Isotypes , Applications FN, Clone 1 KU
5390-0004 NATIVE PIG INTRINSIC FACTOR, Product Type Purified Protein, Specificity INTRINSIC FACTOR, Target Species Pig, Host N_A, Format Purified, Isotypes , Applications FN, Clone 1 KU
5389-9838 MOUSE ANTI PIG INTRINSIC FACTOR, Product Type Monoclonal Antibody, Specificity INTRINSIC FACTOR, Target Species Pig, Host Mouse, Format Purified, Isotypes IgG1, Applications E, Clone 29_011 0.2 mg
SCH-5389-9838 MOUSE ANTI PIG INTRINSIC FACTOR, Product Type Monoclonal Antibody, Specificity INTRINSIC FACTOR, Target Species Pig, Host Mouse, Format Purified, Isotypes IgG1, Applications E, Clone 29_011 0.2 mg
EIAAB09969 460 kDa receptor,Cubilin,Cubn,Glycoprotein 280,gp280,Ifcr,Intrinsic factor-cobalamin receptor,Intrinsic factor-vitamin B12 receptor,Rat,Rattus norvegicus
28-935 PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53_p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and 0.05 mg
CS-1004-03 miRNA Pathway Profiling Cell Array (Notch Pathway, 4 Plates) 4 X 96
CS-1004-05 miRNA Pathway Profiling Cell Array (Wnt b-catenin Pathway, 4 Plates) 4 X 96
CS-1004-02 miRNA Pathway Profiling Cell Array (NFkB Pathway, 4 Plates) 4 X 96
CS-1003-04 miRNA Pathway Profiling Cell Array (MAPK Ras Pathway, 8 Plates) 8 X 96
CS-1003-03 miRNA Pathway Profiling Cell Array (Notch Pathway, 8 Plates) 8 X 96
CS-1003-05 miRNA Pathway Profiling Cell Array (Wnt b-catenin Pathway, 8 Plates) 8 X 96
CS-1003-02 miRNA Pathway Profiling Cell Array (NFkB Pathway, 8 Plates) 8 X 96
CS-1004-01 miRNA Pathway Profiling Cell Array (TGFb Pathway, 4 Plates) 4 X 96
CS-1003-01 miRNA Pathway Profiling Cell Array (TGFb Pathway, 8 Plates) 8 X 96
CS-1004-04 miRNA Pathway Profiling Cell Array (MAPK Ras Pathway, 4 Plates) 4 X 96
10-663-45652 Intrinsic Factor (IF) Human - Intrinsic factor; IF; INF N_A 1 mg
pro-375 Recombinant Human Intrinsic Factor Intrinsic Factor 2
10-663-45652 Intrinsic Factor (IF) Human - Intrinsic factor; IF; INF N_A 0.002 mg

Pathways :

WP1841: Intrinsic Pathway for Apoptosis
WP1783: Apoptosis Meta Pathway
WP1814: Extrinsic Pathway for Apoptosis
WP2272: Pathogenic Escherichia coli infection
WP2328: Allograft rejection
WP2428: the quecetin and apoptosis pathway
WP1: Statin Pathway
WP10: IL-9 Signaling Pathway
WP1004: Kit Receptor Signaling Pathway
WP1010: Wnt Signaling Pathway and Pluripotency
WP1011: T Cell Receptor Signaling Pathway
WP1012: IL-7 Signaling Pathway
WP1014: Androgen receptor signaling pathway
WP1016: Wnt Signaling Pathway
WP1018: Apoptosis
WP1019: FAS pathway and Stress induction of HSP regulation
WP1022: Hedgehog Signaling Pathway
WP1025: B Cell Receptor Signaling Pathway
WP1028: Pentose Phosphate Pathway
WP1029: Notch Signaling Pathway
WP1031: IL-3 Signaling Pathway
WP1033: ACE Inhibitor Pathway
WP1037: p38 MAPK Signaling Pathway
WP1040: Inflammatory Response Pathway
WP1041: Statin Pathway

Related Genes :
[SEPT4 ARTS PNUTL2 SEP4 hucep-7] Septin-4 (Apoptosis-related protein in the TGF-beta signaling pathway) (ARTS) (Bradeion beta) (Brain protein H5) (CE5B3 beta) (Cell division control-related protein 2) (hCDCREL-2) (Cerebral protein 7) (Peanut-like protein 2)
[BIRC2 API1 MIHB RNF48] Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)
[CCAR2 DBC1 KIAA1967] Cell cycle and apoptosis regulator protein 2 (Cell division cycle and apoptosis regulator protein 2) (DBIRD complex subunit KIAA1967) (Deleted in breast cancer gene 1 protein) (DBC-1) (DBC.1) (NET35) (p30 DBC)
[Bok Mtd] Bcl-2-related ovarian killer protein (Apoptosis activator Mtd) (Protein matador)
[Nol3 Arc] Nucleolar protein 3 (Apoptosis repressor with CARD)
[Nol3 Arc] Nucleolar protein 3 (Apoptosis repressor with CARD)
[BCL2] Apoptosis regulator Bcl-2
[BAX BCL2L4] Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4)
[BCL2L1 BCL2L BCLX] Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
[NOL3 ARC NOP] Nucleolar protein 3 (Apoptosis repressor with CARD) (Muscle-enriched cytoplasmic protein) (Myp) (Nucleolar protein of 30 kDa) (Nop30)
[CFLAR CASH CASP8AP1 CLARP MRIT] CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]
[PYCARD ASC CARD5 TMS1] Apoptosis-associated speck-like protein containing a CARD (hASC) (Caspase recruitment domain-containing protein 5) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1)
[Ccar2] Cell cycle and apoptosis regulator protein 2 (Cell division cycle and apoptosis regulator protein 2)
[Birc2] Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2) (RING-type E3 ubiquitin transferase BIRC2)
[PLEKHF1 APPD LAPF ZFYVE15] Pleckstrin homology domain-containing family F member 1 (PH domain-containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (PH and FYVE domain-containing protein 1) (Phafin-1) (Zinc finger FYVE domain-containing protein 15)
[Bax] Apoptosis regulator BAX
[Cflar Cash] CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]
[CUBN IFCR] Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)
[Bcl2 Bcl-2] Apoptosis regulator Bcl-2
[Bax] Apoptosis regulator BAX
[BIRC3 API2 MIHC RNF49] Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
[Pycard Asc] Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein)
[Bcl2l1 Bcl2l Bclx] Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
[BCL2] Apoptosis regulator Bcl-2
[Bbc3 Puma] Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis)
[Diap1 Iap1 th CG12284] Death-associated inhibitor of apoptosis 1 (EC 2.3.2.27) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread) (RING-type E3 ubiquitin transferase Diap1)
[BAX] Apoptosis regulator BAX
[MAP3K5 ASK1 MAPKKK5 MEKK5] Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)
[CBLIF GIF IFMH] Cobalamin binding intrinsic factor (Gastric intrinsic factor) (Intrinsic factor) (IF) (INF)
[BBC3 PUMA] Bcl-2-binding component 3 (JFY-1) (p53 up-regulated modulator of apoptosis)

Bibliography :
[30874970] Secretin Prevents Apoptosis in the Developing Cerebellum Through Bcl-2 and Bcl-xL.
[30867805] Erratum: Adenosine induces intrinsic apoptosis via the PI3K/Akt/mTOR signaling pathway in human pharyngeal squamous carcinoma FaDu cells.
[30867058] Exploiting tumor-intrinsic signals to induce mesenchymal stem cell-mediated suicide gene therapy to fight malignant glioma.
[30861119] Apoptosis and proliferation during human salivary gland development.
[30859632] Tumor suppressor KIF1Bβ regulates mitochondrial apoptosis in collaboration with YME1L1.
[30857974] Ulmosides A: Flavonoid 6-C-glycosides from Ulmus wallichiana attenuates lipopolysacchride induced oxidative stress, apoptosis and neuronal death.
[30849482] Combination treatment of resveratrol and capsaicin radiosensitizes pancreatic tumor cells by unbalancing DNA repair response to radiotherapy towards cell death.
[30843348] Self-assembled lipid nanoparticles for ratiometric codelivery of cisplatin and siRNA targeting XPF to combat drug resistance in lung cancer.
[30842150] Antibiotic Tetrocarcin-A Down-regulates JAM-A, IAPs and Induces Apoptosis in Triple-negative Breast Cancer Models.
[30836847] Pro-apoptotic and pro-proliferation functions of the JNK pathway of Drosophila: roles in cell competition, tumorigenesis and regeneration.