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Response to elevated platelet cytosolic Ca2+

pathways : Response to elevated platelet cytosolic Ca2+ pathways:

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Related Pathways to "Response to elevated platelet cytosolic Ca2+" content :


Related Genes to "Response to elevated platelet cytosolic Ca2+" content :

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Catalog number Product name Quantity
30-811 ECT2 is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of ECT2 is elevated with the onset of DNA synthesis and remains elevated 0.05 mg
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25-272 The heat-shock response is elicited by exposure of cells to thermal and chemical stress and through the activation of HSFs (heat shock factors) results in the elevated expression of heat-shock induced 0.05 mg
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EIAAB06775 Cenpi,CENP-I,Centromere protein I,Follicle-stimulating hormone primary response protein,FSH primary response protein 1,Fshprh1,Leucine-rich primary response protein 1,Lrpr1,Rat,Rattus norvegicus
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Pathways :

WP1903: Response to elevated platelet cytosolic Ca2+
WP1819: Formation of Platelet plug
WP525: Mitochondrial Unfolded-Protein Response
WP710: DNA damage response (only ATM dependent)
WP1883: Platelet Adhesion to exposed collagen
WP997: Cytokines and Inflammatory Response (BioCarta)
WP1113: Cytokines and Inflammatory Response
WP2087: miRNA regulation of DNA Damage Response
WP271: Cytokines and Inflammatory Response (BioCarta)
WP1530: miRNA regulation of DNA Damage Response
WP1815: Factors involved in megakaryocyte development and platelet production
WP458: Inflammatory Response Pathway
WP707: DNA damage response
WP1882: Platelet Activation
WP1885: Platelet homeostasis
WP920: Inflammatory Response Pathway
WP1040: Inflammatory Response Pathway
WP1970: Glycoprotein VI platelet signaling
WP222: Cytokines and Inflammatory Response (BioCarta)
WP1527: stress response
WP1810: Elevation of cytosolic Ca2+ levels
WP453: Inflammatory Response Pathway
WP530: Cytokines and Inflammatory Response
WP1881: Platelet activation triggers
WP1884: Platelet Aggregation (Plug Formation)

Related Genes :
[ATP2A2 ATP2B] Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
[Adcy8] Adenylate cyclase type 8 (EC 4.6.1.1) (ATP pyrophosphate-lyase 8) (Adenylate cyclase type VIII) (Adenylyl cyclase 8) (Ca(2+)/calmodulin-activated adenylyl cyclase)
[CA2] Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II)
[ATP2A3] Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 7.2.2.10) (Calcium pump 3)
[ATP2A1] Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (SERCA1) (SR Ca(2+)-ATPase 1) (EC 7.2.2.10) (Calcium pump 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
[Slc8a1 Ncx1] Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)
[Slc8a3 Ncx3] Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3)
[Slc8a3 Ncx3] Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3)
[] Phospholipase A2 homolog crotoxin acid subunit CA (CTX subunit CA) (Crotapotin) [Cleaved into: Crotoxin chain alpha CA1, CA2 and CA4; Crotoxin chain alpha CA3; Crotoxin chain beta CA2, CA3 and CA4; Crotoxin chain beta CA1; Crotoxin chain gamma (Analgesic peptide) (Crotalphine)]
[SLC8A3 NCX3] Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3)
[Pdgfrb Pdgfr Pdgfr1] Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
[SLC25A24 APC1 MCSC1 SCAMC1] Calcium-binding mitochondrial carrier protein SCaMC-1 (Mitochondrial ATP-Mg/Pi carrier protein 1) (Mitochondrial Ca(2+)-dependent solute carrier protein 1) (Small calcium-binding mitochondrial carrier protein 1) (Solute carrier family 25 member 24)
[SLC8B1 NCKX6 NCLX SLC24A6] Mitochondrial sodium/calcium exchanger protein (Na(+)/K(+)/Ca(2+)-exchange protein 6) (Sodium/calcium exchanger protein, mitochondrial) (Sodium/potassium/calcium exchanger 6) (Solute carrier family 24 member 6) (Solute carrier family 8 member B1)
[Slc8b1 Nckx6 Nclx Slc24a6] Mitochondrial sodium/calcium exchanger protein (Na(+)/K(+)/Ca(2+)-exchange protein 6) (Sodium/calcium exchanger protein, mitochondrial) (Sodium/potassium/calcium exchanger 6) (Solute carrier family 24 member 6) (Solute carrier family 8 member B1)
[ADCY5] Adenylate cyclase type 5 (EC 4.6.1.1) (ATP pyrophosphate-lyase 5) (Adenylate cyclase type V) (Adenylyl cyclase 5) (Ca(2+)-inhibitable adenylyl cyclase)
[Adcy8] Adenylate cyclase type 8 (EC 4.6.1.1) (ATP pyrophosphate-lyase 8) (Adenylate cyclase type VIII) (Adenylyl cyclase 8) (Ca(2+)/calmodulin-activated adenylyl cyclase)
[Slc8b1 Nckx6 Nclx Slc24a6] Mitochondrial sodium/calcium exchanger protein (Na(+)/K(+)/Ca(2+)-exchange protein 6) (Sodium/calcium exchanger protein, mitochondrial) (Sodium/potassium/calcium exchanger 6) (Solute carrier family 24 member 6) (Solute carrier family 8 member B1)
[SLC24A1 KIAA0702 NCKX1] Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger) (Solute carrier family 24 member 1)
[ADCY6 KIAA0422] Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase)
[PDGFRA PDGFR2 RHEPDGFRA] Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
[Pdgfra] Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (Platelet-derived growth factor alpha receptor) (CD antigen CD140a)
[Pdgfra] Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (Platelet-derived growth factor alpha receptor) (CD antigen CD140a)
[cda] Calcium-transporting ATPase (EC 7.2.2.10) (Ca(2+)-ATPase) (Calcium pump) (Calcium-dependent ATPase)
[NCL At1g53210 F12M16.12] Sodium/calcium exchanger NCL (Na(+)/Ca(2+)-exchange protein NCL) (Protein NCX-like) (AtNCL)
[ADCY1] Adenylate cyclase type 1 (EC 4.6.1.1) (ATP pyrophosphate-lyase 1) (Adenylate cyclase type I) (Adenylyl cyclase 1) (AC1) (Ca(2+)/calmodulin-activated adenylyl cyclase)
[chaA yfkE BSU07920] Ca(2+)/H(+) antiporter ChaA
[PDGFRB PDGFR PDGFR1] Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
[SLC24A5 JSX NCKX5] Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Solute carrier family 24 member 5)
[Adcy6] Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (AC6) (Ca(2+)-inhibitable adenylyl cyclase)
[Slc24a4 Nckx4] Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4)

Bibliography :
[25238069] A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis.
[22031597] PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells.
[18209568] Antiplatelet activity of epigallocatechin gallate is mediated by the inhibition of PLCgamma2 phosphorylation, elevation of PGD2 production, and maintaining calcium-ATPase activity.
[17053161] Adenosine inhibits cytosolic calcium signals and chemotaxis in hepatic stellate cells.
[16928598] Endogenously generated reactive oxygen species reduce PMCA activity in platelets from patients with non-insulin-dependent diabetes mellitus.
[16899933] Persistence of the altered polymorphonuclear leukocyte rheological and metabolic variables after 12 months in juvenile myocardial infarction.
[16685463] Low ethanol intake prevents salt-induced hypertension in WKY rats.
[12529741] Thrombin-induced hyperactivity of platelets of young stroke patients: involvement of thrombin receptors in the subject-dependent variability in Ca2+ signal generation.
[10064008] Secreted dense granule adenine nucleotides promote calcium influx and the maintenance of elevated cytosolic calcium levels in stimulated human platelets.
[9575886] Downregulation of nitric oxide synthase in chronic renal insufficiency: role of excess PTH.