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Signal regulatory protein (SIRP) family interactions

pathways : Signal regulatory protein (SIRP) family interactions pathways:

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Related products :

Catalog number Product name Quantity
EIAAB38503 CD172 antigen-like family member B,Homo sapiens,Human,Signal-regulatory protein beta-2,Signal-regulatory protein gamma,SIRPB2,SIRP-b2,SIRP-beta-2,SIRPG,SIRP-gamma
EIAAB38325 Bos taurus,Bovine,CD172 antigen-like family member A,Inhibitory receptor SHPS-1,MYD1,MyD-1 antigen,PTPNS1,SHP substrate 1,SHPS1,SHPS-1,Signal-regulatory protein alpha-1,SIRP,SIRPA,Sirp-alpha-1,Tyrosin
EIAAB38499 CD172 antigen-like family member B,Homo sapiens,Human,Signal-regulatory protein beta-1,SIRPB1,SIRP-beta-1
15-288-21487 Tyrosine-protein phosphatase non-receptor type substrate 1 - SHP substrate 1; SHPS-1; Inhibitory receptor SHPS-1; Signal-regulatory protein alpha-1; Sirp-alpha-1; Sirp-alpha-2; Sirp-alpha-3; MyD-1 ant 0.1 mg
18-661-15013 Tyrosine-protein phosphatase non-receptor type substrate 1 - SHP substrate 1; SHPS-1; Inhibitory receptor SHPS-1; Signal-regulatory protein alpha-1; Sirp-alpha-1; Sirp-alpha-2; Sirp-alpha-3; MyD-1 ant 0.1 mg
15-288-21487 Tyrosine-protein phosphatase non-receptor type substrate 1 - SHP substrate 1; SHPS-1; Inhibitory receptor SHPS-1; Signal-regulatory protein alpha-1; Sirp-alpha-1; Sirp-alpha-2; Sirp-alpha-3; MyD-1 ant 0.05 mg
YSRTMCA620PE SIRP (Signal Regulatory Protein), Clone ED9, Mab anti_Rat, RPE; flow vial
ACL041PE Mouse SIRP (Signal Regulatory Protein), Clone OX_41, Mab anti_, PE 50 µg.
ACL041A Mouse SIRP (Signal Regulatory Protein), Clone OX_41, Mab anti_ 0.5 ml.
YSRTMCA620R SIRP (Signal Regulatory Protein), Clone ED9, Mab anti_Rat, frozen_paraffin, IH_flow_WB 0.25 mg.
T-3002.0250 CD172a _ Clone OX41 Signal Regulatory Protein; SIRP 250ìg
T-3002.0250 CD172a _ Clone OX41 Signal Regulatory Protein; SIRP 250
ACL041PE-4 Mouse SIRP (Signal Regulatory Protein), Clone OX_41, Mab anti_, PE 200 µg.
ACL041AP Mouse SIRP (Signal Regulatory Protein), Clone OX_41, Mab anti_ 250 µg.
YSRTMCA620F SIRP (Signal Regulatory Protein), Clone ED9, Mab anti_Rat, FITC; flow 0.1 mg.
ACL041B-5 Mouse SIRP (Signal Regulatory Protein), Clone OX_41, Mab anti_, Biotin 500 µg.
ACL041B Mouse SIRP (Signal Regulatory Protein), Clone OX_41, Mab anti_, Biotin 100 µg.
ACL041F Mouse SIRP (Signal Regulatory Protein), Clone OX_41, Mab anti_, FITC 100 µg.
YSRTMCA274B CD172a, SIRP (Signal Regulatory Protein), Clone MRC OX_41, Mab anti_Rat, Biotin 0.1 mg.
ACL041F-5 Mouse SIRP (Signal Regulatory Protein), Clone OX_41, Mab anti_, FITC 500 µg.
BMDV10029 SIRP 1 (Signal Regulatory Protein), SHPS_1, BIT, p84, 65_90kD, Rabbit anti_Human, Monkey, NO X w_Mouse; paraffin, IH_WB 0.5 ml.
YSRTMCA274PE Rat OX_41 Antigen, SIRP (Signal Regulatory Protein), Clone MRC OX_41, Mab anti_, RPE 100 tests
YSRTMCA274F Rat OX_41 Antigen, SIRP (Signal Regulatory Protein), Clone MRC OX_41, Mab anti_, FITC 0.1 mg.
YSRTMCA274R Rat OX_41 Antigen, SIRP (Signal Regulatory Protein), Clone MRC OX_41, Mab anti_; frozen_paraffin, IH_flow_WB 0.25 mg.
YSRTMCA274GA Rat OX_41 Antigen, SIRP (Signal Regulatory Protein), Clone MRC OX_41, Mab anti_; frozen_paraffin, IH_flow_WB 0.1 mg.

Pathways :

WP1909: Signal regulatory protein (SIRP) family interactions
WP1493: Carbon assimilation C4 pathway
WP731: Sterol regulatory element binding protein related
WP1485: Interactions between CFTR and other ion channels
WP1689: Porphyrin and chlorophyll metabolism
WP2272: Pathogenic Escherichia coli infection
WP1624: Bacterial secretion system
WP1867: Nephrin interactions
WP962: Signal Transduction of S1P
WP1049: G Protein Signaling Pathways
WP1901: Regulatory RNA pathways
WP1198: Signal Transduction of S1P
WP1693: Purine metabolism
WP2324: AGE/RAGE pathway
WP1650: Fluorobenzoate degradation
WP346: Protein Modifications
WP1659: Glycine, serine and threonine metabolism
WP1391: Signal Transduction of S1P
WP1713: Two-component system
WP1794: Cell surface interactions at the vascular wall
WP57: Signal Transduction of S1P Receptor
WP1665: Limonene and pinene degradation
WP201: Ptf1a related regulatory pathway
WP1675: Nitrogen metabolism
WP211: BMP signaling pathway

Related Genes :
[SIRPA BIT MFR MYD1 PTPNS1 SHPS1 SIRP] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a)
[SIRPG SIRPB2] Signal-regulatory protein gamma (SIRP-gamma) (CD172 antigen-like family member B) (Signal-regulatory protein beta-2) (SIRP-b2) (SIRP-beta-2) (CD antigen CD172g)
[Sirpa Bit Myd1 Ptpns1 Shps1 Sirp] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (p84) (CD antigen CD172a)
[SIRPB1] Signal-regulatory protein beta-1 (SIRP-beta-1) (CD172 antigen-like family member B) (CD antigen CD172b)
[SIRPA MYD1 PTPNS1 SHPS1 SIRP] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (CD antigen CD172a)
[Sirpa Bit Mfr Ptpns1 Shps1 Sirp] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (Macrophage membrane protein MFP150) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (CD antigen CD172a)
[SIRPB2 PTPN1L PTPNS1L3] Signal-regulatory protein beta-2 (SIRP-beta-2) (Protein tyrosine phosphatase non-receptor type substrate 1-like 3) (Protein tyrosine phosphatase non-receptor type substrate protein)
[SIRPB1] Signal-regulatory protein beta-1 isoform 3 (SIRP-beta-1 isoform 3)
[BABAM1 C19orf62 MERIT40 NBA1 HSPC142] BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex)
[SLC9A3R1 NHERF NHERF1] Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
[IGBP1 IBP1] Immunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16)
[Igbp1 Pc52] Immunoglobulin-binding protein 1 (Alpha4 phosphoprotein) (CD79a-binding protein 1) (Lymphocyte signal transduction molecule alpha 4) (Protein phosphatase 2/4/6 regulatory subunit) (p52)
[sirP] Nonribosomal peptide synthetase sirP (NRPS sirP) (EC 6.3.2.-) (Sirodesmin biosynthesis protein P)
[Slc9a3r1 Nherf Nherf1] Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
[PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3] Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3) (Sporulation-induced transcript 4-associated protein SAPL)
[PPP6R1 KIAA1115 PP6R1 SAPS1] Serine/threonine-protein phosphatase 6 regulatory subunit 1 (SAPS domain family member 1)
[PPP6R2 KIAA0685 PP6R2 SAPS2] Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)
[ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730] Zinc finger CCCH domain-containing protein 15 (DRG family-regulatory protein 1) (Likely ortholog of mouse immediate early response erythropoietin 4)
[ABCA1 ABC1 CERP] Phospholipid-transporting ATPase ABCA1 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 1) (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein)
[SIRP1 Os05g0488800 LOC_Os05g40980 OJ1119_H02.11 OsJ_19008] E3 ubiquitin-protein ligase SIRP1 (EC 2.3.2.27) (Salt-induced RING finger protein 1) (OsSIRP1)
[PIK3R1 GRB1] Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
[PIK3R2] Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
[MKNK2 GPRK7 MNK2] MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)
[PSMD2 TRAP2] 26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
[PSMD4 MCB1] 26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein)
[MAPK1 ERK2 PRKM1 PRKM2] Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
[GAL11 ABE1 MED15 RAR3 SDS4 SPT13 YOL051W] Mediator of RNA polymerase II transcription subunit 15 (Autonomous replication regulatory protein 3) (Basal expression activator protein 1) (Defective silencing suppressor protein 4) (Mediator complex subunit 15) (Transcription regulatory protein GAL11) (Ty insertion suppressor protein 13)
[PSMD1] 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)
[TRAF6 RNF85] TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
[MAPK3 ERK1 PRKM3] Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Bibliography :
[24215318] The interaction between signal regulatory protein alpha (SIRPα) and CD47: structure, function, and therapeutic target.
[18657508] Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47.
[17070842] Functional elements on SIRPalpha IgV domain mediate cell surface binding to CD47.
[16691243] The SIRP family of receptors and immune regulation.
[10962556] Inhibition of EGFR-mediated phosphoinositide-3-OH kinase (PI3-K) signaling and glioblastoma phenotype by signal-regulatory proteins (SIRPs).
[9062191] A family of proteins that inhibit signalling through tyrosine kinase receptors.