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Thrombin signalling through proteinase activated receptors (PARs)

pathways : Thrombin signalling through proteinase activated receptors (PARs) pathways:

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Related products :

Catalog number Product name Quantity
PC-PAR1 Proteinase activated receptor1 (Thrombin receptor), WB control 100-150ul
P-PAR1 Proteinase activated receptor1 (Thrombin receptor), Antigen blocking peptide 100ul
H-8365.0005 TRAP_6 Salt Trifluoroacetate Binding _ Synonym SFLLRN, Thrombin Receptor Activator Peptide 6, Thrombin Receptor (1_6) (human), Proteinase Activated Receptor 1 (1_6) (human), PAR_1 (1_6) (human), Co 5.0 mg
H-2234.0025 TRAP_7 Salt Trifluoroacetate Binding _ Synonym Proteinase Activated Receptor 1 (1_7) (human), Thrombin Receptor (1_7) (human), SFLLRNP, Thrombin Receptor Activator Peptide 7, PAR_1 (1_7) (human), C 25.0 mg
H-2234.0005 TRAP_7 Salt Trifluoroacetate Binding _ Synonym Proteinase Activated Receptor 1 (1_7) (human), Thrombin Receptor (1_7) (human), SFLLRNP, Thrombin Receptor Activator Peptide 7, PAR_1 (1_7) (human), C 5.0 mg
H-8365.0005 TRAP_6 Salt Trifluoroacetate Binding _ Synonym SFLLRN, Thrombin Receptor Activator Peptide 6, Thrombin Receptor (1_6) (human), Proteinase Activated Receptor 1 (1_6) (human), PAR_1 (1_6) (human), Co 5.0 mg
H-8365.0025 TRAP_6 Salt Trifluoroacetate Binding _ Synonym SFLLRN, Thrombin Receptor Activator Peptide 6, Thrombin Receptor (1_6) (human), Proteinase Activated Receptor 1 (1_6) (human), PAR_1 (1_6) (human), Co 25.0 mg
H-2234.0025 TRAP_7 Salt Trifluoroacetate Binding _ Synonym Proteinase Activated Receptor 1 (1_7) (human), Thrombin Receptor (1_7) (human), SFLLRNP, Thrombin Receptor Activator Peptide 7, PAR_1 (1_7) (human), C 25.0 mg
H-8365.0025 TRAP_6 Salt Trifluoroacetate Binding _ Synonym SFLLRN, Thrombin Receptor Activator Peptide 6, Thrombin Receptor (1_6) (human), Proteinase Activated Receptor 1 (1_6) (human), PAR_1 (1_6) (human), Co 25.0 mg
H-2234.0005 TRAP_7 Salt Trifluoroacetate Binding _ Synonym Proteinase Activated Receptor 1 (1_7) (human), Thrombin Receptor (1_7) (human), SFLLRNP, Thrombin Receptor Activator Peptide 7, PAR_1 (1_7) (human), C 5.0 mg
PAR1-101AP Proteinase activated receptor1 (Thrombin receptor), Host species: Rabbit, Polyclonal antibody 200ul
PAR1-101AP Proteinase activated receptor1 (Thrombin receptor) Polyclonal anbtibody Host: Rabbit Affinity purifed 200ul
PAR1-101AP Polyclonal Antibody Proteinase activated receptor1 (Thrombin receptor) Immunogen: peptide Host: Rabbit 200ul
H-2938.0100 TRAP_5 amide Salt Trifluoroacetate Binding _ Synonym SFLLRamide, PAR_1 (1_5) amide (human), Thrombin Receptor Activator Peptide 5 amide, Thrombin Receptor (1_5) amide (human), Proteinase Activated 100.0 mg
H-2938.0100 TRAP_5 amide Salt Trifluoroacetate Binding _ Synonym SFLLRamide, PAR_1 (1_5) amide (human), Thrombin Receptor Activator Peptide 5 amide, Thrombin Receptor (1_5) amide (human), Proteinase Activated 100.0 mg
H-2938.0025 TRAP_5 amide Salt Trifluoroacetate Binding _ Synonym SFLLRamide, PAR_1 (1_5) amide (human), Thrombin Receptor Activator Peptide 5 amide, Thrombin Receptor (1_5) amide (human), Proteinase Activated 25.0 mg
H-2938.0025 TRAP_5 amide Salt Trifluoroacetate Binding _ Synonym SFLLRamide, PAR_1 (1_5) amide (human), Thrombin Receptor Activator Peptide 5 amide, Thrombin Receptor (1_5) amide (human), Proteinase Activated 25.0 mg
H-8105.0005 TRAP_14 Salt Trifluoroacetate Binding _ Synonym SFLLRNPNDKYEPF, Thrombin Receptor (1_14) (human), Thrombin Receptor Activator Peptide 14, Proteinase Activated Receptor 1 (1_14) (human), PAR_1 (1_14 5.0 mg
H-8105.0001 TRAP_14 Salt Trifluoroacetate Binding _ Synonym SFLLRNPNDKYEPF, Thrombin Receptor (1_14) (human), Thrombin Receptor Activator Peptide 14, Proteinase Activated Receptor 1 (1_14) (human), PAR_1 (1_14 1.0 mg
H-8105.0005 TRAP_14 Salt Trifluoroacetate Binding _ Synonym SFLLRNPNDKYEPF, Thrombin Receptor (1_14) (human), Thrombin Receptor Activator Peptide 14, Proteinase Activated Receptor 1 (1_14) (human), PAR_1 (1_14 5.0 mg
H-8105.0001 TRAP_14 Salt Trifluoroacetate Binding _ Synonym SFLLRNPNDKYEPF, Thrombin Receptor (1_14) (human), Thrombin Receptor Activator Peptide 14, Proteinase Activated Receptor 1 (1_14) (human), PAR_1 (1_14 1.0 mg
PAR1-101AP Proteinase activated receptor1 (Thrombin receptor) Polyclonal Antibody Host Species: Rabbit Immunogen: peptide Epitope Location: 200ul
PAR1-Biotin Proteinase activated receptor1 (Thrombin receptor), Biotin conjugates 200ul
P-PAR2 Proteinase activated receptor 2 (Thrombin like receptor 1), Antigen blocking peptide 100ul
PAR1-FITC Proteinase activated receptor1 (Thrombin receptor), FITC conjugates 200ul

Pathways :

WP1929: Thrombin signalling through proteinase activated receptors (PARs)
WP1873: NGF signalling via TRKA from the plasma membrane
WP1068: Nuclear Receptors
WP868: estrogen signalling
WP1184: Nuclear Receptors
WP986: estrogen signalling
WP1976: Signalling by NGF
WP217: Nuclear Receptors
WP1244: estrogen signalling
WP1330: estrogen signalling
WP299: Nuclear receptors in lipid metabolism and toxicity
WP755: Nuclear receptors in lipid metabolism and toxicity
WP1425: BMP signalling and regulation
WP1823: GP1b-IX-V activation signalling
WP863: Nuclear receptors in lipid metabolism and toxicity
WP981: Nuclear receptors in lipid metabolism and toxicity
WP1104: estrogen signalling
WP1225: estrogen signalling
WP1982: SREBP signalling
WP272: Blood Clotting Cascade
WP1326: Nuclear receptors in lipid metabolism and toxicity
WP139: Nuclear receptors in lipid metabolism and toxicity
WP509: Nuclear Receptors
WP831: Nuclear Receptors
WP170: Nuclear Receptors

Related Genes :
[F2RL3 PAR4] Proteinase-activated receptor 4 (PAR-4) (Coagulation factor II receptor-like 3) (Thrombin receptor-like 3)
[F2RL1 GPR11 PAR2] Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2]
[F2rl1 Gpcr11 Gpr11 Par2] Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1)
[F2rl1 Par2] Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (Thrombin receptor-like 1)
[F2rl3 Par4] Proteinase-activated receptor 4 (PAR-4) (Coagulation factor II receptor-like 3) (Thrombin receptor-like 3)
[F2] Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]
[F2rl3 Par4] Proteinase-activated receptor 4 (PAR-4) (Coagulation factor II receptor-like 3) (Thrombin receptor-like 3)
[F2RL1 PAR2] Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (Thrombin receptor-like 1)
[MAPK1 ERK2 PRKM1 PRKM2] Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
[Mapk1 Erk2 Mapk Prkm1] Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
[Mapk1 Erk2 Mapk Prkm1] Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
[MAPK3 ERK1 PRKM3] Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)
[Mapk3 Erk1 Prkm3] Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (MNK1) (Microtubule-associated protein 2 kinase) (p44-ERK1)
[Mapk3 Erk1 Prkm3] Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (MNK1) (Microtubule-associated protein 2 kinase) (p44-ERK1)
[] Thrombin-like enzyme cerastocytin (SVTLE) (EC 3.4.21.-) (C.cerastes platelet proaggregant protein) (CC-PPP) (Factor VIII activator) (Fibrinogen-clotting enzyme) (Proaggregant serine proteinase) (Snake venom serine protease) (SVSP)
[Arrb1] Beta-arrestin-1 (Arrestin beta-1)
[ARRB1 ARR1] Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
[Arrb1] Beta-arrestin-1 (Arrestin beta-1)
[SRC SRC1] Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
[ARRB2 ARB2 ARR2] Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
[Src] Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
[GNAQ GAQ] Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q)
[Src] Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
[src] Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
[SRC] Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
[Arrb2] Beta-arrestin-2 (Arrestin beta-2)
[GNA11 GA11] Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha)
[Arrb2] Beta-arrestin-2 (Arrestin beta-2)
[GNB5] Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)
[KNG1 BDK KNG] Kininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into: Kininogen-1 heavy chain; T-kinin (Ile-Ser-Bradykinin); Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II); Kininogen-1 light chain; Low molecular weight growth-promoting factor]
Bibliography :
[34831181] Coagulation Factor Xa Induces Proinflammatory Responses in Cardiac Fibroblasts via Activation of Protease-Activated Receptor-1.
[34502257] Protease Activated Receptors and Arthritis.
[27383574] Protease-activated receptors - biology and role in cancer.
[27068977] Proteinase-activated receptors (PARs) as targets for antiplatelet therapy.
[26770977] Natural Hirudin Increases Rat Flap Viability by Anti-Inflammation via PARs/p38/NF-κB Pathway.
[26569550] Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα.
[25689283] Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis.
[25373316] Proteinase-activated receptor 1- and 4-promoted migration of Hep3B hepatocellular carcinoma cells depends on ROS formation and RTK transactivation.
[24990498] Protease-activated receptor signalling by coagulation proteases in endothelial cells.
[24902855] PAR1-dependent COX-2/PGE2 production contributes to cell proliferation via EP2 receptors in primary human cardiomyocytes.