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Purine metabolism

pathways : Purine metabolism pathways:

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Catalog number Product name Quantity
29-910 SLC29A2 mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. It is less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyrida 0.1 mg
28-189 FOXK2 contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) pr 0.05 mg
26-316 HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monoph 0.05 mg
31-177 FOXK2 contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) pr 0.1 mg
25-576 FOXK2 contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) pr 0.05 mg
30-413 HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monoph 0.05 mg
19690-23-4 2_Amino_6_iodo purine 2_Amino_6_iodo purine 1g
QAH-BMA-1000-2 Human Bone Metabolism Array Q1000 Antibody Arrays Bone Metabolism Arrays 16-22 Sample Kit
QAH-BMA-1000-4 Human Bone Metabolism Array Q1000 Antibody Arrays Bone Metabolism Arrays 32-50 Sample Kit
QAH-BMA-1000-1 Human Bone Metabolism Array Q1000 Antibody Arrays Bone Metabolism Arrays 1-8 Sample Kit
QAH-BMA-1-4 Human Bone Metabolism Array Q1 Antibody Arrays Bone Metabolism Arrays 32-50 Sample Kit
QAH-BMA-2-2 Human Bone Metabolism Array Q2 Antibody Arrays Bone Metabolism Arrays 16-22 Sample Kit
QAH-BMA-1-2 Human Bone Metabolism Array Q1 Antibody Arrays Bone Metabolism Arrays 16-22 Sample Kit
QAH-BMA-1-1 Human Bone Metabolism Array Q1 Antibody Arrays Bone Metabolism Arrays 1-8 Sample Kit
QAH-BMA-2-4 Human Bone Metabolism Array Q2 Antibody Arrays Bone Metabolism Arrays 32-50 Sample Kit
QAH-BMA-2-1 Human Bone Metabolism Array Q2 Antibody Arrays Bone Metabolism Arrays 1-8 Sample Kit
443-72-1 6_(Methylamino)purine 6_(Methylamino)purine 1g
P28960 Purine 500 MG
P28960 Purine 100 MG
P28960 Purine 100 MG
P28960 Purine 500 MG
BB0743 6-Benzylamino purine 25g
CP054-010 6-(y,y-dimethylallylamino)purine (2ip) 10g
120-73-0 Purine 7H-Imidazo(4,5-D)pyri 1g
BB0743 6_Benzylamino purine 25G

Pathways :

WP2185: Purine metabolism
WP2184: Purine metabolism
WP1693: Purine metabolism
WP1817: Fatty acid, triacylglycerol, and ketone body metabolism
WP270: Tryptophan metabolism
WP79: Tryptophan metabolism
WP1169: Estrogen metabolism
WP1617: Alanine, aspartate and glutamate metabolism
WP1690: Propanoate metabolism
WP1893: Pyruvate metabolism and Citric Acid (TCA) cycle
WP495: Glucocorticoid & Mineralcorticoid Metabolism
WP993: Arylamine metabolism
WP100: Glutathione metabolism
WP1355: One Carbon Metabolism
WP1648: Fatty acid metabolism
WP203: De Novo Biosynthesis of Purine Nucleotides
WP549: Galactose Metabolism
WP1038: Vitamin A and carotenoid metabolism
WP139: Nuclear receptors in lipid metabolism and toxicity
WP1656: Glutathione metabolism
WP1848: Metabolism of carbohydrates
WP305: Glucocorticoid Metabolism
WP816: Estrogen metabolism
WP1203: One Carbon Metabolism
WP1621: Arginine and proline metabolism

Related Genes :
[Lacc1 Famin] Purine nucleoside phosphorylase LACC1 (EC 2.4.2.1) (Adenosine deaminase LACC1) (EC 3.5.4.4) (Fatty acid metabolism-immunity nexus) (Guanosine phosphorylase LACC1) (Laccase domain-containing protein 1) (S-methyl-5'-thioadenosine phosphorylase LACC1) (EC 2.4.2.28)
[LACC1 C13orf31 FAMIN] Purine nucleoside phosphorylase LACC1 (EC 2.4.2.1) (Adenosine deaminase LACC1) (EC 3.5.4.4) (Fatty acid metabolism-immunity nexus) (Guanosine phosphorylase LACC1) (Laccase domain-containing protein 1) (S-methyl-5'-thioadenosine phosphorylase LACC1) (EC 2.4.2.28)
[xapA pndA b2407 JW2398] Purine nucleoside phosphorylase 2 (EC 2.4.2.1) (Inosine-guanosine phosphorylase) (Purine nucleoside phosphorylase II) (PNP II) (Xanthosine phosphorylase)
[ATIC PURH OK/SW-cl.86] Bifunctional purine biosynthesis protein ATIC (AICAR transformylase/inosine monophosphate cyclohydrolase) (ATIC) [Cleaved into: Bifunctional purine biosynthesis protein ATIC, N-terminally processed] [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR formyltransferase) (AICAR transformylase); Inosine 5'-monophosphate cyclohydrolase (IMP cyclohydrolase) (EC 3.5.4.10) (IMP synthase) (Inosinicase)]
[yjjX b4394 JW5801] Inosine/xanthosine triphosphatase (ITPase/XTPase) (EC 3.6.1.73) (Non-canonical purine NTP phosphatase) (Non-standard purine NTP phosphatase) (Nucleoside-triphosphate phosphatase) (NTPase)
[rdgB yggV b2954 JW2921] dITP/XTP pyrophosphatase (EC 3.6.1.66) (Deoxyribonucleoside triphosphate pyrophosphohydrolase) (Inosine triphosphate pyrophosphatase) (ITPase) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase)
[ITPA C20orf37 My049 OK/SW-cl.9] Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.9) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase) (Putative oncogene protein hlc14-06-p)
[MJ0226] dITP/XTP pyrophosphatase (EC 3.6.1.66) (Hypoxanthine/xanthine dNTP pyrophosphatase) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase) (Nucleotide triphosphatase)
[HAM1 YJR069C J1811] Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.9) (Hydroxylaminopurine sensitivity protein 1) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase)
[Itpa] Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.9) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase)
[GART PGFT PRGS] Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)]
[Gart ade3 CG31628] Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)]
[Gart] Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)]
[PNP NP] Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)
[PNP PF3D7_0513300] Purine nucleoside phosphorylase (EC 2.4.2.1) (PfPNP) (S-methyl-5'-thioinosine phosphorylase) (EC 2.4.2.44)
[Atic Purh] Bifunctional purine biosynthesis protein ATIC (AICAR transformylase/inosine monophosphate cyclohydrolase) (ATIC) [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (IMP synthase) (Inosinicase)]
[ATIC PURH] Bifunctional purine biosynthesis protein ATIC (AICAR transformylase/inosine monophosphate cyclohydrolase) (ATIC) [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (IMP synthase) (Inosinicase)]
[Atic Purh] Bifunctional purine biosynthesis protein ATIC (AICAR transformylase/inosine monophosphate cyclohydrolase) (ATIC) [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (IMP synthase) (Inosinicase)]
[NT5C2 NT5B NT5CP PNT5] Cytosolic purine 5'-nucleotidase (EC 3.1.3.5) (Cytosolic 5'-nucleotidase II)
[PF0853] Probable 6-oxopurine nucleoside phosphorylase (EC 2.4.2.1) (Purine nucleoside phosphorylase) (PNP) (PfPNP)
[Pnp Np Pnp1] Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)
[Pnp Np] Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)
[purR b1658 JW1650] HTH-type transcriptional repressor PurR (Pur regulon repressor) (Purine nucleotide synthesis repressor)
[GART] Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)]
[GART] Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)]
[ade3 gart GA16345] Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)]
[pnp AgaP_AGAP005945] Purine nucleoside phosphorylase (EC 2.4.2.1) (AgPNP) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)
[Gart rCG_58778] Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)]
[NCS1 PLUTO At5g03555 F12E4.350] Purine-uracil permease NCS1 (Nucleobase cation symporter 1) (AtNCS1) (Plastidic nucleobase transporter) (Uracil/purine transport protein NCS1)
[FCY2 YER056C] Purine-cytosine permease FCY2 (PCP FCY2) (Cytosine/purine transport protein FCY2) (Fluorocytosine resistance protein 2)
Bibliography :
[34666225] Profound inhibition of CD73-dependent formation of anti-inflammatory adenosine in B cells of SLE patients.
[34664585] Toxic effects of copper on the jejunum and colon of pigs: mechanisms related to gut barrier dysfunction and inflammation influenced by the gut microbiota.
[34658219] [Toxic effects of sublethal acetochlor with sublethal doses on earthworms in soil using multi-endpoints system].
[34647753] Metabolomics Analysis of the Effect of GAT-2 Deficiency on Th1 Cells in Mice.
[34646134] Upregulation of Thymidylate Synthase Induces Pemetrexed Resistance in Malignant Pleural Mesothelioma.
[34645877] Untargeted metabolomics reveals sex-specific differences in lipid metabolism of adult rats exposed to dexamethasone in utero.
[34643162] New insights in research on purine and pyrimidine metabolism.
[34638828] Metabolic Analysis of the Development of the Plant-Parasitic Cyst Nematodes and by Capillary Electrophoresis Time-of-Flight Mass Spectrometry.
[34636387] FGF-2 induces a failure of cell cycle progression in cells harboring amplified K-Ras, revealing new insights into oncogene-induced senescence.
[34635103] Emerging roles of dysregulated adenosine homeostasis in brain disorders with a specific focus on neurodegenerative diseases.