GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

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Catalog number Product name Quantity
29-002 NR2E3 is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as w 0.1 mg
27-721 The protein encoded by COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure 0.05 mg
30-467 The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca (2+) signaling pathways. 0.1 mg
26-436 SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. It attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably throu 0.05 mg
3377 (CT) An intermediate in the TLR and Bmp signaling pathways 0.1 mg
3405 (IN2) An intermediate in the TLR and Bmp signaling pathways 0.5 mg
3405 (IN2) An intermediate in the TLR and Bmp signaling pathways 0.1 mg
3377 (CT) An intermediate in the TLR and Bmp signaling pathways 0.5 mg
30-252 Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several 0.05 mg
27-100 COPS4 is one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP 0.05 mg
25-589 Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. 0.05 mg
25-587 Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. 0.05 mg
orb80834 Human NCK2 protein The NCK family of SH2_SH3 adaptor proteins consists of two members, NCK1 and NCK2, which couple tyrosine kinase signaling, including the EGF and PDGF receptor-pathways, to downstrea 2
25-651 Electron transport pathways are generally associated with mitochondrial membranes, but non-mitochondrial pathways are also biologically significant. Plasma membrane electron transport pathways are inv 0.05 mg
30-276 GDE1 has glycerophosphoinositol phosphodiesterase activity. It has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways. 0.05 mg
26-276 TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and 0.05 mg
28-619 Khdrbs1 functions as a transcriptional repressor and may link cellular signaling pathways with components of the transcriptional machinery. It shuttles between the nucleus and the cytoplasm in seconda 0.1 mg
31-010 CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fib 0.05 mg
27-502 Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth 0.1 mg
25-434 RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region fo 0.05 mg
32-151 FER (fer tyrosine kinase) is a member of the FPS_FES family of nontransmembrane receptor tyrosine kinases, which shares a functional domain and is involved in signaling pathways through receptor tyros 0.1 mL
28-922 SMAD1 belongs to the SMAD family. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. SMAD1 mediates the signals of the bone morphogenetic pro 0.1 mg
28-921 SMAD1 belongs to the SMAD family. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. SMAD1 mediates the signals of the bone morphogenetic pro 0.1 mg
27-473 SMAD1 belongs to the SMAD family. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. SMAD1 mediates the signals of the bone morphogenetic pro 0.05 mg
orb61374 Tofacitinib Tofacitinib is a novel Janus kinase 3 (JAK3) inhibitor. JAK3 is a critical cytoplasmic tyrosine kinase in the signaling pathways of multiple cytokines (interleukin (IL)-2, -7, -15 and -21) 50 mg

Pathways :

WP1049: G Protein Signaling Pathways
WP1165: G Protein Signaling Pathways
WP1371: G Protein Signaling Pathways
WP232: G Protein Signaling Pathways
WP35: G Protein Signaling Pathways
WP73: G Protein Signaling Pathways
WP813: G Protein Signaling Pathways
WP931: G Protein Signaling Pathways
WP2032: TSH signaling pathway
WP211: BMP signaling pathway
WP2203: TSLP Signaling Pathway
WP2261: Signaling Pathways in Glioblastoma
WP2272: Pathogenic Escherichia coli infection
WP2292: Chemokine signaling pathway
WP10: IL-9 Signaling Pathway
WP1004: Kit Receptor Signaling Pathway
WP1010: Wnt Signaling Pathway and Pluripotency
WP1011: T Cell Receptor Signaling Pathway
WP1012: IL-7 Signaling Pathway
WP1014: Androgen receptor signaling pathway
WP1016: Wnt Signaling Pathway
WP1017: Type II interferon signaling (IFNG)
WP1022: Hedgehog Signaling Pathway
WP1025: B Cell Receptor Signaling Pathway
WP1029: Notch Signaling Pathway

Related Genes :
[Gpsm1 Ags3] G-protein-signaling modulator 1 (Activator of G-protein signaling 3)
[RGS20 RGSZ1 ZGAP1] Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP) (Regulator of G-protein signaling Z1) (Regulator of Gz-selective protein signaling 1)
[MAVS IPS1 KIAA1271 VISA] Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
[RGS16 RGSR] Regulator of G-protein signaling 16 (RGS16) (A28-RGS14P) (Retinal-specific RGS) (RGS-r) (hRGS-r) (Retinally abundant regulator of G-protein signaling)
[Rgs14] Regulator of G-protein signaling 14 (RGS14)
[Gpsm1 Ags3 C10a] G-protein-signaling modulator 1 (Activator of G-protein signaling 3)
[GPSM1 AGS3] G-protein-signaling modulator 1 (Activator of G-protein signaling 3)
[Mavs Ips1 Visa] Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Virus-induced-signaling adapter) (VISA)
[Sh2b1 Sh2bpsm1] SH2B adapter protein 1 (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2 domain-containing protein 1B) (SH2-B PH domain-containing signaling mediator 1)
[Shh Hhg1] Sonic hedgehog protein (SHH) (HHG-1) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp) (Sonic hedgehog protein 19 kDa product)]
[Rgs14] Regulator of G-protein signaling 14 (RGS14) (RAP1/RAP2-interacting protein) (RPIP1)
[RGS2 G0S8 GIG31] Regulator of G-protein signaling 2 (RGS2) (Cell growth-inhibiting gene 31 protein) (G0/G1 switch regulatory protein 8)
[RGS7] Regulator of G-protein signaling 7 (RGS7)
[RGS14] Regulator of G-protein signaling 14 (RGS14)
[Dynlt1 Tctel1 Tctex-1 Tctex1] Dynein light chain Tctex-type 1 (Activator of G-protein signaling 2) (AGS2) (T-complex testis-specific protein 1) (TCTEX-1)
[RGS6] Regulator of G-protein signaling 6 (RGS6) (S914)
[CRY2 PHH1 SEL20 At1g04400 F19P19.14] Cryptochrome-2 (Atcry2) (Blue light photoreceptor) (Protein PHR homolog 1) (AtPHH1) (Protein SUPPRESSOR OF elf3 20)
[Rgs17 Rgsz2] Regulator of G-protein signaling 17 (RGS17) (Regulator of Gz-selective protein signaling 2)
[Rgs16 Rgsr] Regulator of G-protein signaling 16 (RGS16) (A28-RGS14P) (Retinal-specific RGS) (RGS-r) (Retinally abundant regulator of G-protein signaling)
[GPSM2 LGN] G-protein-signaling modulator 2 (Mosaic protein LGN)
[SHO1 SSU81 YER118C] High osmolarity signaling protein SHO1 (Osmosensor SHO1) (Suppressor of SUA8-1 mutation) (Synthetic high osmolarity-sensitive protein 1)
[RGS1 At3g26090 MPE11.27 MPE11.28] Regulator of G-protein signaling 1 (AtRGS1)
[BSK3 RLCK173 Os04g0684200 LOC_Os04g58750 OsJ_16683 OSJNBa0088H09.6] Probable serine/threonine-protein kinase BSK3 (EC 2.7.11.1) (Brassinosteroid-signaling kinase 3) (OsBSK3) (Receptor-like cytoplasmic kinase 173) (OsRLCK173)
[Rgs20 Rgsz1] Regulator of G-protein signaling 20 (RGS20) (Regulator of G-protein signaling Z1)
[SMAD1 BSP1 MADH1 MADR1] Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1)
[GPSM3 AGS4 C6orf9 G18] G-protein-signaling modulator 3 (Activator of G-protein signaling 4) (G18.1b) (Protein G18)
[CISH G18] Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Protein G18) (Suppressor of cytokine signaling) (SOCS)
[SH2B1 KIAA1299 SH2B] SH2B adapter protein 1 (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2 domain-containing protein 1B)
[IRE1A IRE1-2 At2g17520 MJB20.8] Serine/threonine-protein kinase/endoribonuclease IRE1a (Endoplasmic reticulum-to-nucleus signaling 1-2) (Inositol-requiring protein 1-2) (AtIRE1-2) (Serine/threonine-protein kinase/endoribonuclease IRE1-2) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]
[IRE1B IRE1-1 At5g24360 K16H17.7] Serine/threonine-protein kinase/endoribonuclease IRE1b (Endoplasmic reticulum-to-nucleus signaling 1-1) (Inositol-requiring protein 1-1) (AtIRE1-1) (Serine/threonine-protein kinase/endoribonuclease IRE1-1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]

Bibliography :
[30896156] Exploring Endocytosis and Intracellular Trafficking of the Human Serotonin Receptor.
[30894814] Therapeutic Potential of Targeting ß-Arrestin.
[30893849] Early Transcriptional Response to DNA Virus Infection in .
[30889865] Mechanism of Rapid Nuclear Factor-E2-Related Factor 2 (Nrf2) Activation via Membrane-Associated Estrogen Receptors: Roles of NADPH Oxidase 1, Neutral Sphingomyelinase 2 and Epidermal Growth Factor Receptor (EGFR).
[30881497] Identification of key pathways and candidate genes in pancreatic ductal adenocarcinoma using bioinformatics analysis.
[30880365] The Utilization of Mu-Opioid Receptor Biased Agonists: Oliceridine, an Opioid Analgesic with Reduced Adverse Effects.
[30875275] The salt-sensitive transcriptome of isolated kidney distal tubule cells.
[30875219] Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D1 Receptor Agonists.
[30873601] Cholecystokinin (CCK) Regulation of Pancreatic Acinar Cells: Physiological Actions and Signal Transduction Mechanisms.
[30869808] Functional activation of Gα protein via α -adrenoceptor in rat cerebral cortical membranes.