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Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

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30-188 Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC, one of the last enzymes in this pathway, converts phosphopan 0.1 mg
30-888 The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. CHKA is the initial enzyme in the sequence and may play a regulatory role. It also catalyzes the phosp 0.05 mg
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30-413 HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monoph 0.05 mg
26-316 HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monoph 0.05 mg
29-697 Squalene epoxidase catalyzes the first oxygenation step in sterol biosynthesis and is thought to be one of the rate-limiting enzymes in this pathway. 0.05 mg
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Pathways :

WP2341: vitamin B1 (thiamin) biosynthesis and salvage pathway
WP2340: Thiamine (vitamin B1) biosynthesis and salvage
WP2344: vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) biosynthesis and salvage pathway
WP2345: vitamin B7 (biotin) biosynthesis pathway
WP2353: vitamin B9 (folate) biosynthesis pathway
WP2339: vitamin B2 (riboflavin) biosynthesis and conversion to FMN and FAD pathway
WP2349: vitamin B3 (niacin), NAD and NADP biosynthesis pathway
WP2347: vitamin B5 (pantothenate) and CoA biosynthesis Pathway
WP95: Salvage Pathways of Pyrimidine Ribonucleotides
WP1718: Vitamin B6 metabolism
WP171: NAD Salvage Pathway
WP2316: PPAR signaling pathway
WP1130: T Cell Receptor Signaling Pathway
WP2235: Sulfide oxidation pathway
WP974: IL-9 Signaling Pathway
WP120: Phenylalanine and Tyrosine Biosynthesis
WP2380: BDNF signaling pathway
WP339: ESC Pluripotency Pathways
WP1345: T Cell Receptor Signaling Pathway
WP298: G13 Signaling Pathway
WP626: Abscisic Acid Biosynthesis
WP15: Selenium Pathway
WP387: IL-6 signaling Pathway
WP779: Wnt Signaling Pathway and Pluripotency
WP1783: Apoptosis Meta Pathway

Related Genes :
[] Genome polyprotein (EC 2.7.7.48) (EC 3.4.22.28) (EC 3.4.22.46) (EC 3.6.1.15) (Genome-linked protein VPg1) (Genome-linked protein VPg2) (Genome-linked protein VPg3) (Leader protease) (P1A) (P1B) (P1C) (P1D) (P52) (P56A) (Picornain 3C) (Protease 3C) (Protease P20B) (Protein 2A) (Protein 2C) (Protein 3A) (Protein 3B-1) (Protein 3B-2) (Protein 3B-3) (RNA-directed RNA polymerase 3D-POL) (VP4-VP2) (Virion protein 1) (Virion protein 2) (Virion protein 3) (Virion protein 4) (protein 2B)
[LCB1 EMB2779 FBR11 At4g36480 AP22 C7A10.880] Long chain base biosynthesis protein 1 (AtLCB1) (EC 2.3.1.50) (Protein EMBRYO DEFECTIVE 2779) (Protein FUMONISIN B1 RESISTANT 11)
[CYP27B1 CYP1ALPHA CYP27B] 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (EC 1.14.15.18) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) 1-alpha-hydroxylase) (VD3 1A hydroxylase) (Calcidiol 1-monooxygenase) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome P450C1 alpha) (Cytochrome P450VD1-alpha) (Cytochrome p450 27B1)
[ptsJ STM2436] Vitamin B6 salvage pathway transcriptional repressor PtsJ (HTH-type transcriptional regulatory protein PtsJ)
[Cyp27b1 Cyp27b Cyp40] 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (EC 1.14.15.18) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) 1-alpha-hydroxylase) (VD3 1A hydroxylase) (Calcidiol 1-monooxygenase) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome P450C1 alpha) (Cytochrome P450VD1-alpha) (Cytochrome p450 27B1)
[CYP26B1 CYP26A2 P450RAI2] Cytochrome P450 26B1 (EC 1.14.13.-) (Cytochrome P450 26A2) (Cytochrome P450 retinoic acid-inactivating 2) (Cytochrome P450RAI-2) (Retinoic acid-metabolizing cytochrome)
[Cyp27b1 Cyp27b] 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (EC 1.14.15.18) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) 1-alpha-hydroxylase) (VD3 1A hydroxylase) (Calcidiol 1-monooxygenase) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome P450C1 alpha) (Cytochrome P450VD1-alpha) (Cytochrome p450 27B1)
[ribBA IJ22_23670 PN4B1_04370] Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) (EC 4.1.99.12); GTP cyclohydrolase-2 (EC 3.5.4.25) (GTP cyclohydrolase II)]
[Cyp26b1] Cytochrome P450 26B1 (EC 1.14.13.-) (Cytochrome P450 retinoic acid-inactivating 2) (Cytochrome P450RAI-2)
[fadB clbD_1 clbD_3 A9843_04580 AA954_16095 AB552B1_01200 AB901B6_01873 ABCAM1_0310 B4R90_01270 B9W69_01260 B9X95_11890 BGC29_15795 C2U32_16150 CEJ64_01695 CHQ89_05810 CPI82_06730 DLI67_05615 DOL94_04475 DVA69_00140 E2533_18405 E2535_16845 E2540_09430 EA667_017410 EA685_11140 F4T91_02950 F4U04_06450 F8B16_04030 FD887_00135 FD913_02410 FGL68_03605 FJU42_01160 FJU76_11155 FJU87_01625 FJV14_10540 GSE42_01400 GUK62_00135 LV38_00245 NCTC13420_02652] Fatty acid oxidation complex subunit alpha [Includes: Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17) (EC 5.1.2.3) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]
[cysG cobA AB552B1_03101 FJU87_00155 FJV14_08200 GSE42_16220 SAMEA104305351_00898] Siroheme synthase [Includes: Uroporphyrinogen-III C-methyltransferase (Urogen III methylase) (EC 2.1.1.107) (SUMT) (Uroporphyrinogen III methylase) (UROM); Precorrin-2 dehydrogenase (EC 1.3.1.76); Sirohydrochlorin ferrochelatase (EC 4.99.1.4)]
[Cyp26b1] Cytochrome P450 26B1 (EC 1.14.13.-)
[CYP11B1 S11BH] Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase, CYP11B1) (EC 1.14.15.4)
[Cyp11b1 Cyp11b-1] Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P450(11 beta)-DS) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase, CYP11B1) (EC 1.14.15.4)
[Cyp1b1 Cyp1-b1] Cytochrome P450 1B1 (EC 1.14.14.1) (CYPIB1) (Cytochrome P450CMEF) (Cytochrome P450EF) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
[coaBC PN4B1_11850] Coenzyme A biosynthesis bifunctional protein CoaBC (DNA/pantothenate metabolism flavoprotein) (Phosphopantothenoylcysteine synthetase/decarboxylase) (PPCS-PPCDC) [Includes: Phosphopantothenoylcysteine decarboxylase (PPC decarboxylase) (PPC-DC) (EC 4.1.1.36) (CoaC); Phosphopantothenate--cysteine ligase (EC 6.3.2.5) (CoaB) (Phosphopantothenoylcysteine synthetase) (PPC synthetase) (PPC-S)]
[coaBC A7M79_17635 A7M90_17485 A9843_03125 AA954_04720 AB552B1_03303 AB71191_02536 AB901B6_01999 AB945B12_03969 ABC003_03111 ABCAM1_3185 ABKPCSM17A_02345 ABUW_0529 B4R90_13845 B9W69_07555 B9X95_06205 C2U32_11515 CEJ64_05885 CSB70_3147 DLI69_20260 DVA69_06335 E2533_03370 E2535_02675 E2540_11920 EA667_002825 EA685_06240 EKS29_17040 EWO92_19330 EWO96_19360 EWP49_19465 F8B16_13120 FD913_03560 FDO31_08655 FJU36_09600 FJU42_07085 FJU79_05660 FJV14_07245 G3N45_18735 GNY86_10860 GSE42_17185 GUK62_08985 IX87_11520 LV38_00817 NCTC13305_02991 NCTC13420_03523 SAMEA104305318_01649 SAMEA104305351_01113] Coenzyme A biosynthesis bifunctional protein CoaBC (DNA/pantothenate metabolism flavoprotein) (Phosphopantothenoylcysteine synthetase/decarboxylase) (PPCS-PPCDC) [Includes: Phosphopantothenoylcysteine decarboxylase (PPC decarboxylase) (PPC-DC) (EC 4.1.1.36) (CoaC); Phosphopantothenate--cysteine ligase (EC 6.3.2.5) (CoaB) (Phosphopantothenoylcysteine synthetase) (PPC synthetase) (PPC-S)]
[AKR1B1 ALDR1 ALR2] Aldo-keto reductase family 1 member B1 (EC 1.1.1.300) (EC 1.1.1.372) (EC 1.1.1.54) (Aldehyde reductase) (Aldose reductase) (AR) (EC 1.1.1.21)
[glmU PN4B1_45160] Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)]
[ALDH3B1 ALDH7] Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.28) (EC 1.2.1.5) (EC 1.2.1.7) (Aldehyde dehydrogenase 7)
[glmU A9843_00890 AB552B1_00819 AB945B12_02182 ABKPCSM17A_01841 B4R90_18010 BGC29_12025 C2U32_13795 CHQ89_12925 DLI67_03425 DLI69_01520 DOL94_13605 EA667_000635 EA685_01920 EKS29_19140 F4T91_09110 F4U04_08245 FJU36_16320 FJU42_18350 FJU87_05780 FJV14_02570 G3N45_10000 GSE42_19610 GUK62_12625 IX87_14020 LV38_00268 NCTC13305_02536 SAMEA104305318_00515] Bifunctional protein GlmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)]
[Akr1b1 Akr1b4 Aldr1] Aldo-keto reductase family 1 member B1 (EC 1.1.1.21) (EC 1.1.1.300) (EC 1.1.1.372) (EC 1.1.1.54) (Aldehyde reductase) (Aldose reductase) (AR)
[Akr1b1 Akr1b3 Aldor1 Aldr1 Alr2] Aldo-keto reductase family 1 member B1 (EC 1.1.1.300) (EC 1.1.1.372) (EC 1.1.1.54) (Aldehyde reductase) (Aldo-keto reductase family 1 member B3) (Aldose reductase) (AR) (EC 1.1.1.21)
[Aldh3b1 Aldh7] Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.28) (EC 1.2.1.5) (EC 1.2.1.7) (Aldehyde dehydrogenase 7)
[vdrb nr1i1b gb:dq017633] Vitamin D3 receptor B (VDR-B) (1,25-dihydroxyvitamin D3 receptor B) (Nuclear receptor subfamily 1 group I member 1-B)
[HNRNPA2B1 HNRPA2B1] Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1)
[TPK1] Thiamin pyrophosphokinase 1 (hTPK1) (EC 2.7.6.2) (Placental protein 20) (PP20) (Thiamine pyrophosphokinase 1)
[Aldh3b1] Aldehyde dehydrogenase family 3 member B1 (EC 1.2.1.28) (EC 1.2.1.5) (EC 1.2.1.7)
[Hnrnpa2b1 Hnrnp Hnrpa2b1] Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1)
[Hnrnpa2b1 Hnrpa2b1] Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1)

Bibliography :
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