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Parkinsons Disease Pathway

pathways : Parkinsons Disease Pathway pathways:

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Catalog number Product name Quantity
IPLA-PARK-SER Disease State Samples: Single Donor Human Parkinsons Serum 1ml
IPLA-PARK Disease State Samples: Single Donor Human Parkinsons Plasma 1ml
IPLA-PARK-1ml Single Donor Human Parkinsons Plasma 1ml 1ml
IPLA-PARK-SER-1ml Single Donor Human Parkinsons Serum 1ml 1ml
IPLA-PARK-SER-1ml Single Donor Human Parkinsons Serum 1ml
IPLA-PARK-1ml Single Donor Human Parkinsons Plasma 1ml
CS-1003-04 miRNA Pathway Profiling Cell Array (MAPK Ras Pathway, 8 Plates) 8 X 96
CS-1003-05 miRNA Pathway Profiling Cell Array (Wnt b-catenin Pathway, 8 Plates) 8 X 96
CS-1003-03 miRNA Pathway Profiling Cell Array (Notch Pathway, 8 Plates) 8 X 96
CS-1003-02 miRNA Pathway Profiling Cell Array (NFkB Pathway, 8 Plates) 8 X 96
CS-1004-01 miRNA Pathway Profiling Cell Array (TGFb Pathway, 4 Plates) 4 X 96
CS-1004-03 miRNA Pathway Profiling Cell Array (Notch Pathway, 4 Plates) 4 X 96
CS-1004-04 miRNA Pathway Profiling Cell Array (MAPK Ras Pathway, 4 Plates) 4 X 96
CS-1004-05 miRNA Pathway Profiling Cell Array (Wnt b-catenin Pathway, 4 Plates) 4 X 96
CS-1004-02 miRNA Pathway Profiling Cell Array (NFkB Pathway, 4 Plates) 4 X 96
CS-1003-01 miRNA Pathway Profiling Cell Array (TGFb Pathway, 8 Plates) 8 X 96
30-110 CBS is involved in the transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by this protein. CBS deficiency can cause homocystinuria which affects 0.1 mg
29-978 Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutatio 0.05 mg
30-188 Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC, one of the last enzymes in this pathway, converts phosphopan 0.1 mg
30-888 The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. CHKA is the initial enzyme in the sequence and may play a regulatory role. It also catalyzes the phosp 0.05 mg
26-070 Tryptophan 2,3-dioxygenase (EC 1.13.11.11) plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism. 0.05 mg
30-106 Tryptophan 2,3-dioxygenase (EC 1.13.11.11) plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism. 0.05 mg
CS-1004-05 Frozen cell: miRNA Pathway Profiling Cell Array (Wnt_b-catenin Pathway, 4 Plates) 4 X 96
CS-1003-05 Frozen cell: miRNA Pathway Profiling Cell Array (Wnt_b-catenin Pathway, 8 Plates) 8 X 96
CS-1003-03 Frozen cell: miRNA Pathway Profiling Cell Array (Notch Pathway, 8 Plates) 8 X 96

Pathways :

WP2371: Parkinsons Disease Pathway
WP858: IL-6 Signaling Pathway
WP118: IL-7 Signaling Pathway
WP946: Delta-Notch Signaling Pathway
WP1348: Androgen Receptor Signaling Pathway
WP2412: New Pathway
WP17: daf-2 or insulin signaling pathway
WP366: TGF beta Signaling Pathway
WP2139: Practical assignment pathway
WP480: T Cell Receptor Signaling Pathway
WP1770: One carbon metabolism and related pathways
WP2353: vitamin B9 (folate) biosynthesis pathway
WP668: Octadecanoid Pathway
WP1040: Inflammatory Response Pathway
WP801: ACE Inhibitor Pathway
WP1147: Pentose Phosphate Pathway
WP911: Pentose Phosphate Pathway
WP1299: ErbB signaling pathway
WP112: Principle Pathways of Carbon Metabolism
WP1381: G13 Signaling Pathway
WP294: p38 MAPK Signaling Pathway (BioCarta)
WP2018: RANKL/RANK Signaling Pathway
WP400: p38 MAPK Signaling Pathway
WP229: Irinotecan Pathway
WP539: Wnt Signaling Pathway NetPath

Related Genes :
[DTX47 EDS5 IAP1 SCORD3 SID1 At4g39030 F19H22.130] Protein DETOXIFICATION 47, chloroplastic (AtDTX47) (Multidrug and toxic compound extrusion protein 47) (MATE protein 47) (Protein ENHANCED DISEASE SUSCEPTIBILITY 5) (Protein EDS5) (Protein IMPORTANT FOR THE ARR PATHWAY 1) (Protein IAP1) (Protein SALICYLIC ACID INDUCTION DEFICIENT 1) (Protein SID1) (Protein SUSCEPTIBLE TO CORONATINE-DEFICIENT PST DC3000 3) (Protein SCORD3)
[PRKN PARK2] E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
[PKD2 TRPP2] Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2)
[PARK7 CAP1] Parkinson disease protein 7 homolog (Contraception-associated protein 1) (Maillard deglycase) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) [Cleaved into: Parkinson disease protein 7 homolog, N-terminally processed]
[RPS4 At5g45250 K9E15.1] Disease resistance protein RPS4 (Probable NAD(+) hydrolase RPS4) (EC 3.2.2.6) (Resistance to Pseudomonas syringae 4) (TIR-NBS-LRR class disease resistance protein)
[COL17A1 BP180 BPAG2] Collagen alpha-1(XVII) chain (180 kDa bullous pemphigoid antigen 2) (Bullous pemphigoid antigen 2) [Cleaved into: 120 kDa linear IgA disease antigen (120 kDa linear IgA dermatosis antigen) (Linear IgA disease antigen 1) (LAD-1); 97 kDa linear IgA disease antigen (97 kDa linear IgA bullous dermatosis antigen) (97 kDa LAD antigen) (97-LAD) (Linear IgA bullous disease antigen of 97 kDa) (LABD97)]
[RRS1 RCH2 RRS1-S RSH4 SLH1 WRKY52 At5g45260/At5g45270 K9E15.2/K9E15.3] Disease resistance protein RRS1 (Disease resistance protein RCH2) (Disease resistance protein SLH1) (Probable WRKY transcription factor 52) (Protein RPS4-homolog) (Protein SENSITIVE TO LOW HUMIDITY 1) (Resistance to Colletotrichum higginsianum 2 protein) (Resistance to Ralstonia solanacearum 1 protein) (WRKY DNA-binding protein 52)
[APP A4 AD1] Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]
[PARK7] Parkinson disease protein 7 (Maillard deglycase) (Oncogene DJ1) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124)
[NOD2 CARD15 IBD1] Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) (Inflammatory bowel disease protein 1)
[NDP EVR2] Norrin (Norrie disease protein) (X-linked exudative vitreoretinopathy 2 protein)
[PAD4 EDS9 At3g52430 F22O6.190] Lipase-like PAD4 (EC 2.3.1.-) (Protein ENHANCED DISEASE SUSCEPTIBILITY 9) (Protein PHYTOALEXIN DEFICIENT 4) (AtPAD4)
[VHL] von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
[PKD1] Polycystin-1 (PC1) (Autosomal dominant polycystic kidney disease 1 protein)
[App] Amyloid-beta A4 protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) (Amyloid precursor protein) (Amyloid-beta precursor protein) (Amyloidogenic glycoprotein) (AG) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99) (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (APP-C59) (Amyloid intracellular domain 59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (APP-C57) (Amyloid intracellular domain 57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AID(50)) (Gamma-CTF(50)); C31]
[CLN3 BTS] Battenin (Batten disease protein) (Protein CLN3)
[Park7] Parkinson disease protein 7 homolog (Maillard deglycase) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124)
[ATXN3 ATX3 MJD MJD1 SCA3] Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein)
[EDR1 STY10 At1g08720 F22O13.20] Serine/threonine-protein kinase EDR1 (EC 2.7.11.1) (MAPKK kinase EDR1) (Protein ENHANCED DISEASE RESISTANCE 1) (AtEDR1) (Serine/threonine/tyrosine-protein kinase 10)
[Vhl Vhlh] von Hippel-Lindau disease tumor suppressor (pVHL)
[Pkd2 TRPP2] Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2)
[App] Amyloid-beta A4 protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) (Amyloid precursor protein) (Amyloid-beta precursor protein) (Amyloidogenic glycoprotein) (AG) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Gamma-CTF(50)); C31]
[NCF1 NOXO2 SH3PXD1A] Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)
[Ift88 Tg737 Tg737Rpw TgN737Rpw Ttc10] Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (TgN(Imorpk)737Rpw)
[Ndp Ndph] Norrin (Norrie disease protein homolog)
[SUMM2 At1g12280 F5O11.3] Disease resistance protein SUMM2 (Disease resistance protein At1g12280) (Protein SUPPRESSOR OF MKK1 MKK2 2)
[Htt Hd Hdh] Huntingtin (Huntington disease protein homolog) (HD protein homolog) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
[Park7 Cap1] Parkinson disease protein 7 homolog (Contraception-associated protein 1) (Protein CAP1) (Fertility protein SP22) (Maillard deglycase) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124)
[PARK7] Parkinson disease protein 7 homolog (Maillard deglycase) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124)
[Vhl] von Hippel-Lindau disease tumor suppressor (pVHL)
Bibliography :
[32611232] The protective effect of decoction of Rehmanniae via PI3K/Akt/mTOR pathway in MPP-induced Parkinson's disease model cells.
[32607746] Enhancing the Activity of Glucocerebrosidase as a Treatment for Parkinson Disease.
[32601912] Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease.
[32599671] Dopamine Depletion induces Neuron-specific Alterations of GABAergic Transmission in the Mouse Striatum.
[32590036] GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming.
[32580013] A novel pyrazolo [3,4-d] pyrimidine, KKC080106, activates the Nrf2 pathway and protects nigral dopaminergic neurons.
[32558966] A computational model-based analysis of basal ganglia pathway changes in Parkinson's disease inferred from resting-state fMRI.
[32557853] Meta-Analysis of Gut Dysbiosis in Parkinson's Disease.
[32548924] Proteomic profiling of striatal tissue of a rat model of Parkinson's disease after implantation of collagen-encapsulated human umbilical cord mesenchymal stem cells.
[32517799] Parkinson's disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions.