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Hypertrophy Model

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Pathways :

WP1100: Hypertrophy Model
WP1327: Hypertrophy Model
WP202: Hypertrophy Model
WP442: Hypertrophy Model
WP516: Hypertrophy Model
WP756: Hypertrophy Model
WP864: Hypertrophy Model
WP982: Hypertrophy Model
WP1526: Cardiac Hypertrophy: miR-208
WP1528: Physiological and Pathological Hypertrophy of the Heart
WP1544: MicroRNAs in cardiomyocyte hypertrophy
WP1559: TFs Regulate miRNAs related to cardiac hypertrophy
WP1560: MicroRNAs in cardiomyocyte hypertrophy
WP2080: TFs Regulate miRNAs related to cardiac hypertrophy

Related Genes :
[PRKAG2] 5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2) (H91620p)
[ADRA1A ADRA1C] Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c)
[GATA4] Transcription factor GATA-4 (GATA-binding factor 4)
[MYH7 MYHCB] Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)
[Csrp3 Clp Mlp] Cysteine and glycine-rich protein 3 (Cysteine-rich protein 3) (CRP3) (LIM domain protein, cardiac) (Muscle LIM protein)
[Foxo1 Fkhr Foxo1a] Forkhead box protein O1 (Forkhead box protein O1A) (Forkhead in rhabdomyosarcoma)
[GARS] Glycine--tRNA ligase (EC 3.6.1.17) (EC 6.1.1.14) (Diadenosine tetraphosphate synthetase) (AP-4-A synthetase) (Glycyl-tRNA synthetase) (GlyRS)
[IGF1 IBP1] Insulin-like growth factor I (IGF-I) (Mechano growth factor) (MGF) (Somatomedin-C)
[Corin Crn Lrp4] Atrial natriuretic peptide-converting enzyme (EC 3.4.21.-) (Corin) (Low density lipoprotein receptor-related protein 4) (Pro-ANP-converting enzyme) [Cleaved into: Atrial natriuretic peptide-converting enzyme, N-terminal propeptide; Atrial natriuretic peptide-converting enzyme, activated protease fragment; Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment]
[MYH6 MYHCA] Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha)
[CDK9 CDC2L4 TAK] Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
[Akap13 Brx] A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc)
[Akap13 Rt13] A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc)
[AKAP13 BRX HT31 LBC] A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47)
[RYR2] Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
[Cib1 Cib Kip Prkdcip] Calcium and integrin-binding protein 1 (CIB) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP)
[Glrx3 Picot Txnl2] Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2)
[Camk2d Kiaa4163] Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
[Prkce Pkce] Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)
[Ppp3ca Calna] Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit alpha isoform) (CNA alpha)
[Cib1 Cib Kip Prkdcip] Calcium and integrin-binding protein 1 (CIB) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP)
[CAV3] Caveolin-3 (M-caveolin)
[Cacna1c Cach2 Cacn2 Cacnl1a1 Cchl1a1] Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (MELC-CC) (Mouse brain class C) (MBC) (Voltage-gated calcium channel subunit alpha Cav1.2)
[JPH2 JP2] Junctophilin-2 (JP-2) (Junctophilin type 2) [Cleaved into: Junctophilin-2 N-terminal fragment (JP2NT)]
[Glrx3 Picot Txnl2] Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2)
[Prkd1 Pkcm Pkd Prkcm] Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)
[Prkd1 Pkcm Pkd Prkcm] Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)
[Klf15 Cklf] Krueppel-like factor 15 (Cardiovascular Krueppel-like factor)
[FHL1 SLIM1] Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM-protein 1) (SLIM) (SLIM-1)
[Prkca Pkca] Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)

Bibliography :
[30898653] New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis.
[30898320] Pentamethylquercetin protects against cardiac remodeling via activation of Sestrin2.
[30894457] CXA-10, a Nitrated Fatty Acid, is Renoprotective in Deoxycorticosterone Acetate-Salt Nephropathy.
[30894177] Left ventricular concentric geometry predicts incident diabetes mellitus independent of established risk factors in the general population: the Copenhagen City Heart Study.
[30890839] Assessment of changes in masseter muscle by three-dimensional close-range photogrammetry after Botulinum toxin type-A injection: A case report with review of literature.
[30887214] Inflammation and fibrosis in murine models of heart failure.
[30885241] Hyperoxia-induced lung structure-function relation, vessel rarefaction, and cardiac hypertrophy in an infant rat model.
[30884248] Tsg101 positively regulates physiologic-like cardiac hypertrophy through FIP3-mediated endosomal recycling of IGF-1R.
[30880336] The antioxidant alpha lipoic acid attenuates intermittent hypoxia-related renal injury in a mouse model of sleep apnea.
[30880263] Experimental protocol for development of adjuvant-free murine chronic model of allergic asthma.