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Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Related products :

Catalog number Product name Quantity
D470905 4-[4-[2-(Dimethylamino)ethoxy]diphenylmethyl] Tamoxifen (Tamoxifen EP Impurity H) C43H48N2O2 CAS: 25 mg
orb60752 Tamoxifen Citrate Tamoxifen Citrate(Nolvadex) is an estrogen receptor antagonist with an IC50 of 31 5 mg
orb62270 Tamoxifen citrate Tamoxifen citrate For research use only. 500 g
KI0468 Tamoxifen 250mg
M40103474 Tamoxifen CAS: [10540-29-1] 1 g
T006077 Tamoxifen-d5 C26H24D5NO CAS: 1 mg
T006007 (E_Z)-Tamoxifen-d5 C26H24D5NO CAS: 1 mg
QAH-BMA-1000-2 Human Bone Metabolism Array Q1000 Antibody Arrays Bone Metabolism Arrays 16-22 Sample Kit
QAH-BMA-1000-4 Human Bone Metabolism Array Q1000 Antibody Arrays Bone Metabolism Arrays 32-50 Sample Kit
QAH-BMA-1000-1 Human Bone Metabolism Array Q1000 Antibody Arrays Bone Metabolism Arrays 1-8 Sample Kit
T006000 Tamoxifen C26H29NO CAS: 10540-29-1 2.5 g
D293902 N-Desmethyl Tamoxifen-d5 C25H22D5NO CAS: 1 mg
T006002 Tamoxifen-13C6 C2013C6H29NO CAS: 1 mg
T006010 (E)-Tamoxifen C26H29NO CAS: 13002-65-8 1 mg
32637-74 Tamoxifen Citrate Salt 100MG
T006087 (E,Z)-Tamoxifen-d5 N-β-D-Glucuronide C32H33D5NO7 CAS: 1 mg
1551-1000 Tamoxifen citrate1 g 1 g
H954722 (E)-3-Hydroxy Tamoxifen-d5 C26H24D5NO2 CAS: 1 mg
D452710 (E_Z)-4,4’-Dihydroxy Tamoxifen C26H29NO3 CAS: 10 mg
T006005 (E_Z)-Tamoxifen C26H29NO CAS: 7728-73-6 10 mg
1551-1000 Tamoxifen citrate 1 g
A575075 (E)-4-Alloxycarboxyl Tamoxifen C30H33NO4 CAS: 10 mg
M40103474 Tamoxifen CAS Number [10540_29_1] 1 G
32637-74 Tamoxifen Citrate Salt 100 mg
M77181863 Tamoxifen citrate CAS: [54965-24-1] 1 g

Pathways :

WP845: Tamoxifen metabolism
WP691: Tamoxifen metabolism
WP1169: Estrogen metabolism
WP1617: Alanine, aspartate and glutamate metabolism
WP1690: Propanoate metabolism
WP1893: Pyruvate metabolism and Citric Acid (TCA) cycle
WP549: Galactose Metabolism
WP100: Glutathione metabolism
WP1355: One Carbon Metabolism
WP1648: Fatty acid metabolism
WP1817: Fatty acid, triacylglycerol, and ketone body metabolism
WP28: Selenium Metabolism and Selenoproteins
WP816: Estrogen metabolism
WP139: Nuclear receptors in lipid metabolism and toxicity
WP1656: Glutathione metabolism
WP1848: Metabolism of carbohydrates
WP317: Glycogen Metabolism
WP1203: One Carbon Metabolism
WP1621: Arginine and proline metabolism
WP1695: Pyruvate metabolism
WP2102: Fatty acid metabolism
WP659: Cholesterol metabolism
WP1038: Vitamin A and carotenoid metabolism
WP1631: Biotin metabolism
WP1701: Starch and sucrose metabolism

Related Genes :
[RBFOX2 FOX2 HRNBP2 RBM9 RTA] RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity)
[SCP2] Non-specific lipid-transfer protein (NSL-TP) (EC 2.3.1.176) (Propanoyl-CoA C-acyltransferase) (SCP-chi) (SCPX) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X)
[CYP2D6 CYP2DL1] Cytochrome P450 2D6 (EC 1.14.14.-) (CYPIID6) (Cholesterol 25-hydroxylase) (Cytochrome P450-DB1) (Debrisoquine 4-hydroxylase)
[CYP3A4 CYP3A3] Cytochrome P450 3A4 (EC 1.14.14.1) (1,4-cineole 2-exo-monooxygenase) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.14.56) (Albendazole monooxygenase (sulfoxide-forming)) (EC 1.14.14.73) (Albendazole sulfoxidase) (CYPIIIA3) (CYPIIIA4) (Cholesterol 25-hydroxylase) (Cytochrome P450 3A3) (Cytochrome P450 HLp) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Nifedipine oxidase) (Quinine 3-monooxygenase) (EC 1.14.14.55)
[CYP2C19] Cytochrome P450 2C19 (EC 1.14.14.1) ((R)-limonene 6-monooxygenase) (EC 1.14.14.53) ((S)-limonene 6-monooxygenase) (EC 1.14.14.51) ((S)-limonene 7-monooxygenase) (EC 1.14.14.52) (CYPIIC17) (CYPIIC19) (Cytochrome P450-11A) (Cytochrome P450-254C) (Fenbendazole monooxygenase (4'-hydroxylating)) (EC 1.14.14.75) (Mephenytoin 4-hydroxylase)
[CYP1A1] Cytochrome P450 1A1 (CYPIA1) (EC 1.14.14.1) (Cytochrome P450 form 6) (Cytochrome P450-C) (Cytochrome P450-P1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
[CYP2C9 CYP2C10] Cytochrome P450 2C9 (EC 1.14.14.1) ((R)-limonene 6-monooxygenase) (EC 1.14.14.53) ((S)-limonene 6-monooxygenase) (EC 1.14.14.51) ((S)-limonene 7-monooxygenase) (EC 1.14.14.52) (CYPIIC9) (Cholesterol 25-hydroxylase) (Cytochrome P-450MP) (Cytochrome P450 MP-4) (Cytochrome P450 MP-8) (Cytochrome P450 PB-1) (S-mephenytoin 4-hydroxylase)
[CYP2C8] Cytochrome P450 2C8 (EC 1.14.14.1) (CYPIIC8) (Cytochrome P450 IIC2) (Cytochrome P450 MP-12) (Cytochrome P450 MP-20) (Cytochrome P450 form 1) (S-mephenytoin 4-hydroxylase)
[CYP2J2] Cytochrome P450 2J2 (EC 1.14.14.-) (Albendazole monooxygenase (hydroxylating)) (EC 1.14.14.74) (Albendazole monooxygenase (sulfoxide-forming)) (EC 1.14.14.73) (Arachidonic acid epoxygenase) (CYPIIJ2) (Hydroperoxy icosatetraenoate isomerase) (EC 5.4.4.7)
[CYP1B1] Cytochrome P450 1B1 (EC 1.14.14.1) (CYPIB1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
[CYP2B6] Cytochrome P450 2B6 (EC 1.14.13.-) (1,4-cineole 2-exo-monooxygenase) (CYPIIB6) (Cytochrome P450 IIB1)
[CYP3A5] Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (Cytochrome P450-PCN3)
[CYP2E1 CYP2E] Cytochrome P450 2E1 (EC 1.14.14.1) (4-nitrophenol 2-hydroxylase) (EC 1.14.13.n7) (CYPIIE1) (Cytochrome P450-J)
[EBP] 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EC 5.3.3.5) (Cholestenol Delta-isomerase) (Delta(8)-Delta(7) sterol isomerase) (D8-D7 sterol isomerase) (Emopamil-binding protein)
[CYP3A7] Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (Cytochrome P450-HFLA) (P450HLp2)
[CYP2A6 CYP2A3] Cytochrome P450 2A6 (EC 1.14.13.-) (1,4-cineole 2-exo-monooxygenase) (CYPIIA6) (Coumarin 7-hydroxylase) (Cytochrome P450 IIA3) (Cytochrome P450(I))
[FMO3] Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (EC 1.14.14.73) (Dimethylaniline oxidase 3) (FMO II) (FMO form 2) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Trimethylamine monooxygenase) (EC 1.14.13.148)
[SULT1A1 STP STP1 OK/SW-cl.88] Sulfotransferase 1A1 (ST1A1) (EC 2.8.2.1) (Aryl sulfotransferase 1) (HAST1/HAST2) (Phenol sulfotransferase 1) (Phenol-sulfating phenol sulfotransferase 1) (P-PST 1) (ST1A3) (Thermostable phenol sulfotransferase) (Ts-PST)
[CES1 CES2 SES1] Liver carboxylesterase 1 (Acyl-coenzyme A:cholesterol acyltransferase) (ACAT) (Brain carboxylesterase hBr1) (Carboxylesterase 1) (CE-1) (hCE-1) (EC 3.1.1.1) (Cocaine carboxylesterase) (Egasyn) (HMSE) (Methylumbelliferyl-acetate deacetylase 1) (EC 3.1.1.56) (Monocyte/macrophage serine esterase) (Retinyl ester hydrolase) (REH) (Serine esterase 1) (Triacylglycerol hydrolase) (TGH)
[fadR oleR thdB b1187 JW1176] Fatty acid metabolism regulator protein
[laeA ANIA_00807] Secondary metabolism regulator laeA (Methyltransferase laeA) (EC 2.1.1.-) (Velvet complex subunit laeA)
[TYE7 CAALFM_C113140CA CaO19.12407 CaO19.4941] Carbohydrate metabolism regulator TYE7
[MET4 YNL103W N2177] Transcriptional activator of sulfur metabolism MET4 (Methionine-requiring protein 4)
[kgd Rv1248c] Multifunctional 2-oxoglutarate metabolism enzyme (2-hydroxy-3-oxoadipate synthase) (HOA synthase) (HOAS) (EC 2.2.1.5) (2-oxoglutarate carboxy-lyase) (2-oxoglutarate decarboxylase) (Alpha-ketoglutarate decarboxylase) (KG decarboxylase) (KGD) (EC 4.1.1.71) (Alpha-ketoglutarate-glyoxylate carboligase) [Includes: 2-oxoglutarate dehydrogenase E1 component (ODH E1 component) (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase E1 component) (KDH E1 component); Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex E2 component) (ODH E2 component) (OGDC-E2) (Dihydrolipoamide succinyltransferase)]
[kgd sucA MSMEG_5049 MSMEI_4922] Multifunctional 2-oxoglutarate metabolism enzyme (2-hydroxy-3-oxoadipate synthase) (HOA synthase) (HOAS) (EC 2.2.1.5) (2-oxoglutarate carboxy-lyase) (2-oxoglutarate decarboxylase) (Alpha-ketoglutarate decarboxylase) (KG decarboxylase) (KGD) (EC 4.1.1.71) (Alpha-ketoglutarate-glyoxylate carboligase) [Includes: 2-oxoglutarate dehydrogenase E1 component (ODH E1 component) (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase E1 component) (KDH E1 component); Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex E2 component) (ODH E2 component) (OGDC-E2) (Dihydrolipoamide succinyltransferase)]
[veA ANIA_01052] Developmental and secondary metabolism regulator veA (Velvet complex subunit A)
[GAL80 YML051W YM9827.01 YM9958.12] Galactose/lactose metabolism regulatory protein GAL80
[kgd BCG_1308c] Multifunctional 2-oxoglutarate metabolism enzyme (2-hydroxy-3-oxoadipate synthase) (HOA synthase) (HOAS) (EC 2.2.1.5) (2-oxoglutarate carboxy-lyase) (2-oxoglutarate decarboxylase) (Alpha-ketoglutarate decarboxylase) (KG decarboxylase) (KGD) (EC 4.1.1.71) (Alpha-ketoglutarate-glyoxylate carboligase) [Includes: 2-oxoglutarate dehydrogenase E1 component (ODH E1 component) (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase E1 component) (KDH E1 component); Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex E2 component) (ODH E2 component) (OGDC-E2) (Dihydrolipoamide succinyltransferase)]
[kgd ML1095] Multifunctional 2-oxoglutarate metabolism enzyme (2-hydroxy-3-oxoadipate synthase) (HOA synthase) (HOAS) (EC 2.2.1.5) (2-oxoglutarate carboxy-lyase) (2-oxoglutarate decarboxylase) (Alpha-ketoglutarate decarboxylase) (KG decarboxylase) (KGD) (EC 4.1.1.71) (Alpha-ketoglutarate-glyoxylate carboligase) [Includes: 2-oxoglutarate dehydrogenase E1 component (ODH E1 component) (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase E1 component) (KDH E1 component); Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex E2 component) (ODH E2 component) (OGDC-E2) (Dihydrolipoamide succinyltransferase)]
[kgd MAP_2536] Multifunctional 2-oxoglutarate metabolism enzyme (2-hydroxy-3-oxoadipate synthase) (HOA synthase) (HOAS) (EC 2.2.1.5) (2-oxoglutarate carboxy-lyase) (2-oxoglutarate decarboxylase) (Alpha-ketoglutarate decarboxylase) (KG decarboxylase) (KGD) (EC 4.1.1.71) (Alpha-ketoglutarate-glyoxylate carboligase) [Includes: 2-oxoglutarate dehydrogenase E1 component (ODH E1 component) (EC 1.2.4.2) (Alpha-ketoglutarate dehydrogenase E1 component) (KDH E1 component); Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex E2 component) (ODH E2 component) (OGDC-E2) (Dihydrolipoamide succinyltransferase)]

Bibliography :
[32239553] Estrogen receptor alpha signaling in extrahypothalamic neurons during late puberty decreases bone size and strength in female but not in male mice.
[32171179] Sex steroid hormones differentially regulate CYP2D in female wild-type and CYP2D6-humanized mice.
[32165171] Abundant expression of the membrane-anchored protease-regulator RECK in the anterior pituitary gland and its implication in the growth hormone/insulin-like growth factor 1 axis in mice.
[32154159] Unveiling the Impact of Morphine on Tamoxifen Metabolism in Mice .
[32093392] In Vitro Inhibition of Hsp90 Protein by Benzothiazoloquinazolinequinones Is Enhanced in The Presence of Ascorbate. A Preliminary In Vivo Antiproliferative Study.
[32080081] Tamoxifen-related endocrine symptoms in Chinese patients with breast cancer: Study protocol clinical trial (SPIRIT Compliant).
[32061672] Beneficial effects of tamoxifen on leptin sensitivity in young mice fed a high fat diet: Role of estrogen receptor α and cytokines.
[32047265] Variations and expression features of CYP2D6 contribute to schizophrenia risk.
[32030569] GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models.
[32001260] S-adenosylhomocysteine (AdoHcy)-dependent methyltransferase inhibitor DZNep overcomes breast cancer tamoxifen resistance via induction of NSD2 degradation and suppression of NSD2-driven redox homeostasis.