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Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Related products :

Catalog number Product name Quantity
EIAAB10743 DDIT4L,DNA damage-inducible transcript 4-like protein,HIF-1 responsive protein RTP801-like,Homo sapiens,Human,Protein regulated in development and DNA damage response 2,REDD2,REDD-2,RTP801L
EIAAB10733 Ddit4,Dexamethasone-induced gene 2 protein,Dig2,DNA damage-inducible transcript 4 protein,HIF-1 responsive protein RTP801,Mouse,Mus musculus,Protein regulated in development and DNA damage response 1,
EIAAB10730 Ddit4,DNA damage-inducible transcript 4 protein,HIF-1 responsive protein RTP801,Protein regulated in development and DNA damage response 1,Rat,Rattus norvegicus,Redd1,REDD-1,Rtp801
EIAAB10732 DDIT4,DNA damage-inducible transcript 4 protein,HIF-1 responsive protein RTP801,Homo sapiens,Human,Protein regulated in development and DNA damage response 1,REDD1,REDD-1,RTP801
27-302 RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protei 0.1 mg
25-771 GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucl 0.05 mg
25-772 GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucl 0.05 mg
28-910 TP73 belongs to the p53 family. It participates in the apoptotic response to DNA damage. When overproduced, it activates transcription from p53-responsive promoters and induces apoptosis. TP53 may be 0.1 mg
30-737 PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telang 0.05 mg
27-938 Poly (ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PAR 0.05 mg
25-157 Poly (ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PAR 0.05 mg
27-942 Poly (ADP-ribose) polymerases (PARPs) constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain. They are involved in DNA-damage-dependent post-t 0.1 mg
27-997 Poly (ADP-ribose) polymerases (PARPs) constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain. They are involved in DNA-damage-dependent post-t 0.05 mg
EIAAB32161 GADD34,Growth arrest and DNA damage-inducible protein GADD34,Homo sapiens,Human,Myeloid differentiation primary response protein MyD116 homolog,PPP1R15A,Protein phosphatase 1 regulatory subunit 15A
61-001 anti_E.coli LexA antibody, rabbit serum E. coli LexA protein binds specifically to the SOS_box sequence and represses the genes belonging to the SOS regulon. In response to DNA damage, RecA protein is 50 ul
30-841 HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RA 0.05 mg
61-002 anti_E.coli LexA antibody, rabbit serum E. coli LexA protein binds specifically to the SOS_box sequence and represses the genes belonging to the SOS regulon. In response to DNA damage, RecA protein is 250 ul
27-305 In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. CHEK2 is a cell cycle checkpoint regulator and putative tumor 0.05 mg
EIAAB10707 Damage-specific DNA-binding protein 1,DDB p127 subunit,DDB1,DDBa,DNA damage-binding protein 1,DNA damage-binding protein a,HBV X-associated protein 1,Homo sapiens,Human,UV-damaged DNA-binding factor,U
EIAAB32158 Gadd34,Growth arrest and DNA damage-inducible protein GADD34,Mouse,Mus musculus,Myd116,Myeloid differentiation primary response protein MyD116,Ppp1r15a,Protein phosphatase 1 regulatory subunit 15A
EIAAB32159 Gadd34,Growth arrest and DNA damage-inducible protein GADD34,Myd116,Myeloid differentiation primary response protein MyD116 homolog,Peg3,PEG-3,Ppp1r15a,Progression elevated gene 3 protein,Protein phos
EIAAB39881 Bos taurus,Bovine,Serum response factor-binding protein 1,SRFBP1,SRF-dependent transcription regulation-associated protein
EIAAB39880 p49_STRAP,Rat,Rattus norvegicus,Serum response factor-binding protein 1,Srfbp1,SRF-dependent transcription regulation-associated protein
EIAAB39878 Mouse,Mus musculus,p49_STRAP,Serum response factor-binding protein 1,Srfbp1,SRF-dependent transcription regulation-associated protein
EIAAB39879 Homo sapiens,Human,p49_STRAP,Serum response factor-binding protein 1,SRFBP1,SRF-dependent transcription regulation-associated protein

Pathways :

WP710: DNA damage response (only ATM dependent)
WP1530: miRNA regulation of DNA Damage Response
WP707: DNA damage response
WP2087: miRNA regulation of DNA Damage Response
WP1579: DNA damage response
WP1939: Unfolded Protein Response
WP1040: Inflammatory Response Pathway
WP1493: Carbon assimilation C4 pathway
WP222: Cytokines and Inflammatory Response (BioCarta)
WP40: Inflammatory Response Pathway
WP525: Mitochondrial Unfolded-Protein Response
WP1625: Base excision repair
WP1678: Nucleotide excision repair
WP997: Cytokines and Inflammatory Response (BioCarta)
WP1903: Response to elevated platelet cytosolic Ca2+
WP2152: BDNF
WP1156: Inflammatory Response Pathway
WP1527: stress response
WP271: Cytokines and Inflammatory Response (BioCarta)
WP458: Inflammatory Response Pathway
WP1619: Amino sugar and nucleotide sugar metabolism
WP1676: Non-homologous end-joining
WP920: Inflammatory Response Pathway
WP1804: DNA Damage Reversal
WP1113: Cytokines and Inflammatory Response

Related Genes :
[TEL1 YBL088C YBL0706] Serine/threonine-protein kinase TEL1 (EC 2.7.11.1) (ATM homolog) (DNA-damage checkpoint kinase TEL1) (Telomere length regulation protein 1)
[tel1 SPCC23B6.03c] Serine/threonine-protein kinase tel1 (EC 2.7.11.1) (ATM homolog) (DNA-damage checkpoint kinase tel1) (Telomere length regulation protein 1)
[WSS1 YHR134W] DNA-dependent metalloprotease WSS1 (EC 3.4.24.-) (DNA damage response protein WSS1) (SUMO-dependent isopeptidase WSS1) (Weak suppressor of SMT3 protein 1)
[mus-21 tel1 NCU00274] Serine/threonine-protein kinase tel1 (EC 2.7.11.1) (ATM homolog) (DNA-damage checkpoint kinase tel1) (Telomere length regulation protein 1)
[mdb1 SPAC2E11.14 SPACUNK4.14] DNA damage response protein Mdb1 (BRCT domain protein Mdb1) (Midzone and DNA break-localizing protein 1)
[Ddit4 Dig2 Redd1 Rtp801] DNA damage-inducible transcript 4 protein (Dexamethasone-induced gene 2 protein) (HIF-1 responsive protein RTP801) (Protein regulated in development and DNA damage response 1) (REDD-1)
[MEC1 ESR1 SAD3 YBR136W YBR1012] Serine/threonine-protein kinase MEC1 (EC 2.7.11.1) (ATR homolog) (DNA-damage checkpoint kinase MEC1) (Mitosis entry checkpoint protein 1)
[ATM] Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
[Atm] Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog)
[tefu atm CG6535] Serine/threonine-protein kinase ATM (EC 2.7.11.1) (Telomere fusion protein)
[ATM] Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T mutated homolog)
[BRAT1 BAAT1 C7orf27] BRCA1-associated ATM activator 1 (BRCA1-associated protein required for ATM activation protein 1)
[wss2 wss1b SPCC1442.07c] DNA-dependent metalloprotease WSS1 homolog 2 (EC 3.4.24.-) (DNA damage response protein WSS1 homolog 2)
[SPRTN C1orf124 DVC1 UNQ1880/PRO4323] DNA-dependent metalloprotease SPRTN (EC 3.4.24.-) (DNA damage protein targeting VCP) (DVC1) (Protein with SprT-like domain at the N terminus) (Spartan)
[ATF2 CREB2 CREBP1] Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (HB16) (cAMP response element-binding protein CRE-BP1)
[DDIT4L REDD2 RTP801L] DNA damage-inducible transcript 4-like protein (HIF-1 responsive protein RTP801-like) (Protein regulated in development and DNA damage response 2) (REDD-2)
[Atf2] Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (MXBP protein) (cAMP response element-binding protein CRE-BP1)
[Atf2] Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (cAMP response element-binding protein CRE-BP1)
[TEL1 CNF02070] Serine/threonine-protein kinase TEL1 (EC 2.7.11.1) (ATM homolog) (DNA-damage checkpoint kinase TEL1) (Telomere length regulation protein 1)
[DDB1 XAP1] DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
[tel1 AFUA_5G12660] Serine/threonine-protein kinase tel1 (EC 2.7.11.1) (ATM homolog) (DNA-damage checkpoint kinase tel1) (Telomere length regulation protein 1)
[atl-1 T06E4.3] Serine/threonine-protein kinase ATR (EC 2.7.11.1) (ATM-like protein 1) (Ataxia telangiectasia and Rad3-related protein homolog) (ATR homolog) (Ce-atl-1)
[Atm Atm_mapped rCG_58300] Serine-protein kinase ATM (EC 2.7.11.1)
[PRKDC HYRC HYRC1] DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
[dvc-1 T19B10.6] DNA-dependent metalloprotease dvc-1 (EC 3.4.24.-) (DNA damage protein targeting VCP) (DVC1) (Protein with SprT-like domain at the N terminus) (Spartan)
[ATM] Serine-protein kinase ATM (EC 2.7.11.1)
[Ddb1] DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)
[Atm] Serine-protein kinase ATM (EC 2.7.11.1)
[ATM] Serine-protein kinase ATM (EC 2.7.11.1)
[DDB2] DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)

Bibliography :
[34570618] DNA damage-induced phosphorylation of histone H2A at serine 15 is linked to DNA end resection.
[34400889] p53-dependent apoptosis is essential for the antitumor effect of paclitaxel response to DNA damage in papillary thyroid carcinoma.
[33731502] Inhibition of Crandell-Rees Feline Kidney cell proliferation by X-ray-induced senescence.
[33539011] Aging and Protein Kinases.
[33469661] A DYRK1B-dependent pathway suppresses rDNA transcription in response to DNA damage.
[33288855] Impact of hypoxia on the double-strand break repair after photon and carbon ion irradiation of radioresistant HNSCC cells.
[32868381] Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non-Muscle-Invasive Bladder Cancer.
[32456284] Down-Regulation of miR-23a-3p Mediates Irradiation-Induced Neuronal Apoptosis.
[32290532] Differences in the Response to DNA Double-Strand Breaks between Rod Photoreceptors of Rodents, Pigs, and Humans.
[32186434] Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death.