Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery
Publication Date : //
Biocatalytic procedures offer a good alternative to the chemical synthesis of nucleosides since biocatalyzed reactions are regio- and stereoselective and afford reduced by-products contents. Among them, enzymatic transglycosylation between a pyrimidine nucleoside and a purine base catalyzed by nucleoside phosphorylases or microorganisms that contain them, has attracted considerable attention. In addition, the combination to other enzymatic steps has been explored. In this work we investigate the coupled action of nucleoside phosphorylases with other enzymatic activities: deaminase and phosphopentomutase. Unlike the preparation of other purine nucleosides, transglycosylation from a pyrimidine nucleoside and guanine is difficult because of the low solubility of this base. Therefore, another strategy, based on microbial transglycosylation followed by deamination, is here explored. The direct use of furanose 1-phosphate, the intermediate in the transglycosylation reaction, is an attractive alternative when pyrimidine nucleosides are not available. Its preparation from the more stable furanose 5-phosphate and phosphopentomutase is here applied to different sugars and bases.
Authors : Medici Rosario , Porro Marisa Taverna , Lewkowicz Elizabeth , Montserrat Javier , Iribarren Adolfo M ,
Related products :
52062 Aachen Deutschland
Support Karolina Elandt
Tel: +49 0241 40 08 90 86, +49 0241 95 78 94 78, +49 0241 40 08 90 86
Fax: (+49) 241 56 00 47 88
Logistic :0241 40 08 90 86
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
[email protected] | Gentaur | Gentaur
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123
Canada Montreal +15149077481
Ceská republika Praha +420246019719
Finland Helsset +358942419041
Magyarország Budapest +3619980547
US New York+17185132983
WP101: Synthesis and Degradation of Ketone Bodies
WP1013: Triacylglyceride Synthesis
WP1015: Synthesis and Degradation of Ketone Bodies
WP1034: Acetylcholine Synthesis
WP1090: Eicosanoid Synthesis
WP1111: Prostaglandin Synthesis and Regulation
WP1118: Biogenic Amine Synthesis
WP1132: Triacylglyceride Synthesis
WP1134: Synthesis and Degradation of Ketone Bodies
WP125: Biogenic Amine Synthesis
WP1318: Eicosanoid Synthesis
WP1347: Triacylglyceride Synthesis
WP1531: Vitamin D synthesis
WP154: Biogenic Amine Synthesis
WP167: Eicosanoid Synthesis
WP1706: Synthesis and degradation of ketone bodies
WP175: Acetylcholine Synthesis
WP1830: Insulin Synthesis and Processing
WP1887: Post-translational modification: synthesis of GPI-anchored proteins
WP1902: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
WP1925: Synthesis of DNA
WP1926: Synthesis, Secretion, and Deacylation of Ghrelin
WP1937: Transport of vitamins, nucleosides, and related molecules
WP1945: TCA BCH6203
WP212: Triacylglyceride Synthesis
Related Genes :
 Estrogen Activation by Steroid Sulfatase Increases Colorectal Cancer Proliferation via GPER.
 A Single Deoxynucleoside Kinase Variant from Drosophila melanogaster Synthesizes Monophosphates of Nucleosides That Are Components of an Expanded Genetic System.
 LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
 A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.
 Adenosine A1( )receptors are selectively coupled to Gα(i-3) in postmortem human brain cortex: Guanosine-5'-O-(3-[(35)S]thio)triphosphate ([(35)S]GTPγS) binding/immunoprecipitation study.
 Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues.
 A conformational mimetic approach for the synthesis of carbocyclic nucleosides as anti-HCV leads.
 Discovery of an acyclic nucleoside phosphonate that inhibits Mycobacterium tuberculosis ThyX based on the binding mode of a 5-alkynyl substrate analogue.
 Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids.
 Characterization of compounds and potential neuraminidase inhibitors from the n-butanol extract of Compound Indigowoad Root Granule using ultrafiltration and liquid chromatography-tandem mass spectrometry.
Enter catalog number :