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Pubmed ID :31494992
Publication Date : //

Activation through toll-like receptor 2 on group 2 innate lymphoid cells can induce asthmatic characteristics.


Type 2 innate lymphoid cells (ILC2s) are one of the sources of IL-5 and IL-13 in allergic airway inflammation. Innate immune receptors such as Toll-like receptors (TLRs) expressed on epithelial cells could contribute to ILC2 activation through IL-33 production, but a direct effect of TLRs on ILC2s remains to be elucidated.

Authors : Ishii Takashi , Muroi Masashi , Horiguchi Kazuhide , Tanamoto Ken-Ichi , Nagase Takahide , Yamashita Naomi ,

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