GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

Pubmed ID: 31952247
Publication Date: 2020/01/15

Could Omega 3 Fatty Acids Preserve Muscle Health in Rheumatoid Arthritis?

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by a high prevalence of death due to cardiometabolic diseases. As observed during the aging process, several comorbidities, such as cardiovascular disorders (CVD), insulin resistance, metabolic syndrome and sarcopenia, are frequently associated to RA. These abnormalities could be closely linked to alterations in lipid metabolism. Indeed, RA patients exhibit a lipid paradox, defined by reduced levels of total, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol whereas the CVD risk is increased. Moreover, the accumulation of toxic lipid mediators (i.e., lipotoxicity) in skeletal muscles can induce mitochondrial dysfunctions and insulin resistance, which are both crucial determinants of CVD and sarcopenia. The prevention or reversion of these biological perturbations in RA patients could contribute to the maintenance of muscle health and thus be protective against the increased risk for cardiometabolic diseases, dysmobility and mortality. Yet, several studies have shown that omega 3 fatty acids (FA) could prevent the development of RA, improve muscle metabolism and limit muscle atrophy in obese and insulin-resistant subjects. Thereby, dietary supplementation with omega 3 FA should be a promising strategy to counteract muscle lipotoxicity and for the prevention of comorbidities in RA patients.
Authors: Lanchais Kassandra , Capel Frederic , Tournadre Anne ,


  1. [Last access 2020/01/15].

Related products :

Catalog number Product name Quantity
E13651964 Human Omega-6 fatty acids (ω-6-FA)ELISA Kit 1
E13651977 Human Omega-3 free fatty acids (ω-3-FFA)ELISA Kit 1
E13651976 Human Omega-6 free fatty acids (ω-6-FFA)ELISA Kit 1
EIAAB37320 Augmented in rheumatoid arthritis 1,AURA1,Homo sapiens,Human,OLAH,Oleoyl-ACP hydrolase,S-acyl fatty acid synthase thioesterase, medium chain,THEDC1,Thioesterase domain-containing protein 1,Thioesteras
DRA-123-H Human Sample (Rheumatoid Arthritis) 100 ml